Electrical stimulation of peripheral nerves via implanted electrodes has been shown to be a promising approach to restore sensation, movement, and autonomic functions across a wide range of illnesses and injuries. While in principle computational mod...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2025
Single-cell omics technologies have revolutionized the study of long non-coding RNAs (lncRNAs), offering unprecedented resolution in elucidating their expression dynamics, cell-type specificity, and associated gene regulatory networks (GRNs). Concurr...
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Jan 1, 2025
Medical image analysis based on deep learning is a rapidly advancing field in veterinary diagnostics. The aim of this retrospective diagnostic accuracy study was to develop and assess a convolutional neural network (CNN, EfficientNet) to evaluate elb...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2025
Developmental toxicity is key human health endpoint, especially relevant for safeguarding maternal and child well-being. It is an object of increasing attention from international regulatory bodies such as the US EPA (US Environmental Protection Agen...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2025
Machine learning (ML) has increasingly been applied to predict properties of drugs. Particularly, metabolism can be predicted with ML methods, which can be exploited during drug discovery and development. The prediction of metabolism is a crucial bot...
Toxicological sciences : an official journal of the Society of Toxicology
Jan 1, 2025
Plasma half-life is a crucial pharmacokinetic parameter for estimating extralabel withdrawal intervals of drugs to ensure the safety of food products derived from animals. This study focuses on developing a quantitative structure-activity relationshi...
BACKGROUND: Sanguinarine (SAN) has been reported to have antioxidant, antiinflammatory, and antimicrobial activities with potential for the treatment of osteoporosis (OP).
MOTIVATION: Recent experimental developments enable single-cell multimodal epigenomic profiling, which measures multiple histone modifications and chromatin accessibility within the same cell. Such parallel measurements provide exciting new opportuni...
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Dec 25, 2024
In order to seek a patient friendly and low-cost intestinal examination method, a structurally simple pneumatic soft intestinal robot inspired by inchworms is designed and manufactured. The intestinal robot was consisted of two radially expanding cyl...
Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control
Dec 19, 2024
OBJECTIVE: To predict the areas of snail spread in Anhui Province from 1977 to 2023 using machine learning models, and to compare the effectiveness of different machine learning models for prediction of areas of snail spread, so as to provide insig...
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