Yao xue xue bao = Acta pharmaceutica Sinica
Oct 1, 2015
A series of new pleuromutilins derivatives were designed and synthesized through coupling 2-aminothiazole ring of WL001 with different nitrogen-containing substituted heterocycles in the side chain. Their biological activities were evaluated against ...
African journal of medicine and medical sciences
Jun 1, 2015
BACKGROUND: The current widespread distribution and use of Yoyo bitters; an herbal bitters made in Nigeria calls for an assessment of its content, efficacy and extent to which this product achieves the labelled claim of being an herbal cleanser.
Survival of bacterial populations treated with lethal doses of antibiotics is ensured by the presence of very small numbers of persister cells. Unlike antibiotic-resistant cells, antibiotic tolerance of persisters is not inheritable and reversible. T...
OBJECTIVES: The aim of the current study was to analyze the susceptibility of gram-positive and -negative clinical isolates to a novel des-F(6)-quinolone (nemonoxacin) and other selected antimicrobial agents.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi
Jan 1, 2015
PURPOSE: For the analysis of erythromycin (ER) in topical pharmaceutical forms we developed a high performance liquid chromatography dosage method (HPLC) greatly improved over the method formalized by the European Pharmacopoeia 5th ed.
Combinatorial chemistry & high throughput screening
Jan 1, 2015
The ligand-based virtual screening of combinatorial libraries employs a number of statistical modeling and machine learning methods. A comprehensive analysis of the application of these methods for the diversity oriented virtual screening of biologic...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2015
Bacteria have been one of the world's most dangerous and deadliest pathogens for mankind, nowadays giving rise to significant public health concerns. Given the prevalence of these microbial pathogens and their increasing resistance to existing antibi...
PURPOSE OF REVIEW: Failed opportunities to reduce morbidity and mortality occur when evidence-based therapies are not fully implemented in clinical practice. We reviewed the recent literature on implementation strategies in the intensive care unit, w...