AIMC Topic: Antioxidants
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Optimization of biological activities of Agaricus species: an artificial intelligence-assisted approach.
Scientific reports
Jul 2, 2025
This study aims to determine the optimum extraction conditions that maximize the biological activities of Agaricus campestris and Agaricus bisporus species. In the study, a total of 64 extraction experiments were carried out at different temperatures...
Machine learning optimization of microwave-assisted extraction of phenolics and tannins from pomegranate peel.
Scientific reports
Jun 3, 2025
The peel of pomegranate (Punica granatum) is rich in bioactive compounds, specifically phenolic compounds and tannin compounds. However, there is still a lot of difficulty dealing with the extraction of these substances due to the limitations of trad...
Ecofriendly Extraction of Polyphenols from Leaves Coupled with Response Surface Methodology and Artificial Neural Network-Genetic Algorithm.
Molecules (Basel, Switzerland)
May 28, 2025
This study aimed to optimize a novel deep eutectic solvents (DESs)-assisted extraction process for polyphenols in the leaves of (AGPL) with response surface methodology (RSM) and a genetic algorithm-artificial neural network (GA-ANN). Under the infl...
Variations of the chemical components and biological activities of Thymus capitatus essential oil from three regions in Palestine.
Scientific reports
May 10, 2025
Thymus capitatus is a widely utilized medicinal plant in Palestine. The main goal of this study was to assess the phytochemical content of T. capitatus essential oils (EOs) from three Palestinian regions using hydro-distillation. Furthermore, the EO ...
Effect of PUFAs-ω3 and ω6 on oxidative stress of sheep erythrocytes.
BMC veterinary research
May 10, 2025
BACKGROUND: In recent years, the use of long-chain polyunsaturated fatty acids (PUFA) ω3 and ω6, as food supplements in livestock has increased due to their beneficial properties related to their antioxidant activity. It has been demonstrated however...
Facile phyto-mediated synthesis of ternary CuO/MnO/ZnO nanocomposite using Nigella Sativa seeds extract: characterization,antimicrobial, and biomedical evaluations.
Scientific reports
May 8, 2025
The phyto-synthesis of ternary CuO/ MnO/ZnO nanocomposite was achieved by the utilization of an eco-friendly, straightforward approach that involved the extract of Nigella sativa seeds. Our ternary nanocomposite appears to include equal amounts of Cu...
Optimization of polyphenols extraction by deep eutectic solvent from broccoli stem and characterization of their composition and antioxidative effects.
Scientific reports
May 8, 2025
Broccoli stem is known to possess abundant polyphenols. To efficiently extract polyphenols from broccoli stems, we herein describe an updated deep eutectic solvent extraction (DESE) method. Response surface modeling was utilized for optimization of t...
Mechanism Exploration of Dietary Supplement Astaxanthin on Improving Atherosclerosis through an Integrated Strategy Encompassing Artificial Intelligence Virtual Screening and Experimental Validation.
Journal of agricultural and food chemistry
Apr 23, 2025
Atherosclerosis (AS) is a major and common pathological basis of ischemic intestinal infarction, myocardial infarction, stroke, renal failure, and other highly lethal and disabling diseases. Current pharmacological interventions (e.g., statins) often...
Machine learning modeling and response surface methodology driven antioxidant and anticancer activities of chitosan nanoparticle-mediated extracts of Bacopa monnieri.
International journal of biological macromolecules
Apr 23, 2025
This study investigates the potential of chitosan nanoparticles (CNPs) in enhancing the bioavailability and efficacy of Bacopa monnieri extracts, known for their neuroprotective, antioxidant, and anticancer properties. Different concentrations of CNP...
Preclinical evidence construction for epigallocatechin-3-gallate against non-alcoholic fatty liver disease: a meta-analysis and machine learning study.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Apr 10, 2025
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) has emerged as a significant health concern worldwide, exhibiting an increasing incidence that necessitates immediate intervention. Epigallocatechin-3-gallate (EGCG) has shown significant pharmaco...
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