AIMC Topic: Aortic Aneurysm, Abdominal

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Elucidate senescence-related gene signature and immune infiltration landscape in abdominal aortic aneurysm.

PloS one
BACKGROUND: Abdominal aortic aneurysm (AAA) refers to a lasting enlargement of the abdominal aorta. Senescence, a major risk factor of AAA, demonstrate positive connection with both the formation and rupture of aneurysms. Therefore, investigating the...

Deep learning algorithm for predicting rapid progression of abdominal aortic aneurysm by integrating CT images and clinical features.

Scientific reports
Abdominal aortic aneurysm (AAA) progression carries a significant rupture risk, demanding accurate prediction models beyond traditional methods that rely on limited clinical parameters and often overlook complex factor interplay. We aimed to enhance ...

UCP2 is identified as a therapeutic target for abdominal aortic aneurysm by comprehensive bioinformatic analysis and experimental validation.

Biochemical and biophysical research communications
Abdominal aortic aneurysm (AAA) is a potentially life-threatening vascular condition that currently lacks effective pharmacological treatment. The disease is strongly associated with chronic inflammation, where immune cells like macrophages play a cr...

Revealing potential interfering genes between abdominal aortic aneurysm and periodontitis through machine learning and bioinformatics analysis.

PloS one
This study aimed to identify potential interacting genes between abdominal aortic aneurysm (AAA) and periodontitis. To achieve this, we obtained datasets of AAA and periodontitis from the GEO database, conducted differential analysis on the AAA datas...

Identification and validation of hub genes related to neutrophil extracellular traps-mediated cell damage and immune recruitment during abdominal aortic aneurysm.

Scientific reports
Previous research has shown that the formation of Neutrophil Extracellular Traps (NETs), mediated by neutrophils, leads to an increase in inflammatory cell response and cellular tissue damage during Abdominal Aortic Aneurysm (AAA). Building on this f...

Natural Language Processing framework for identifying abdominal aortic aneurysm repairs using unstructured electronic health records.

Scientific reports
Patient identification for national registries often relies upon clinician recognition of cases or retrospective searches using potentially inaccurate clinical codes, leading to incomplete data capture and inefficiencies. Natural Language Processing ...

Imaging analysis using Artificial Intelligence to predict outcomes after endovascular aortic aneurysm repair: protocol for a retrospective cohort study.

BMJ open
INTRODUCTION: Endovascular aortic aneurysm repair (EVAR) requires long-term surveillance to detect and treat postoperative complications. However, prediction models to optimise follow-up strategies are still lacking. The primary objective of this stu...

Performance assessment of an artificial intelligence algorithm for opportunistic screening of abdominal aortic aneurysms.

Clinical imaging
PURPOSE: Abdominal aortic aneurysm (AAA) is a common incidental finding on CT imaging performed in the acute care setting. Artificial intelligence (AI) algorithms have been developed to automatically measure aortic lumen size and thus facilitate AAA ...

Integrative Analysis of Lactylation-Associated Features in Abdominal Aortic Aneurysm and Its Immune Microenvironment Utilizing scRNA-seq and Bulk RNA Sequencing.

Circulation journal : official journal of the Japanese Circulation Society
BACKGROUND: Abdominal aortic aneurysm (AAA) is a vascular disease strongly associated with immune dysregulation and metabolic disturbances. Although lactate metabolism and its associated process, lactylation, have been implicated in various diseases,...