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Immunoprecipitation

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A novel method for the rapid detection of post-translationally modified visinin-like protein 1 in rat models of brain injury.

Brain injury
BACKGROUND: Although elevated serum levels of visinin-like protein 1 (VILIP-1), a neuron-specific calcium sensor protein, are associated with ischaemic stroke, only a single study has evaluated VILIP-1 as a biomarker of traumatic brain injury (TBI). ...

Prediction model for malignant pulmonary nodules based on cfMeDIP-seq and machine learning.

Cancer science
Cell-free methylated DNA immunoprecipitation and high-throughput sequencing (cfMeDIP-seq) is a new bisulfite-free technique, which can detect the whole-genome methylation of blood cell-free DNA (cfDNA). Using this technique, we identified differentia...

MAGPIE: A Machine Learning Approach to Decipher Protein-Protein Interactions in Human Plasma.

Journal of proteome research
Immunoprecipitation coupled to tandem mass spectrometry (IP-MS/MS) methods are often used to identify protein-protein interactions (PPIs). While these approaches are prone to false positive identifications through contamination and antibody nonspecif...