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Asthma

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Feature engineering with clinical expert knowledge: A case study assessment of machine learning model complexity and performance.

PloS one
Incorporating expert knowledge at the time machine learning models are trained holds promise for producing models that are easier to interpret. The main objectives of this study were to use a feature engineering approach to incorporate clinical exper...

Deep learning approaches for sleep disorder prediction in an asthma cohort.

The Journal of asthma : official journal of the Association for the Care of Asthma
OBJECTIVE: Sleep is a natural activity of humans that affects physical and mental health; therefore, sleep disturbance may lead to fatigue and lower productivity. This study examined 1 million samples included in the Taiwan National Health Insurance ...

A modern approach to identifying and characterizing child asthma and wheeze phenotypes based on clinical data.

PloS one
'Asthma' is a complex disease that encapsulates a heterogeneous group of phenotypes and endotypes. Research to understand these phenotypes has previously been based on longitudinal wheeze patterns or hypothesis-driven observational criteria. The aim ...

Machine learning approach to single nucleotide polymorphism-based asthma prediction.

PloS one
Machine learning (ML) is poised as a transformational approach uniquely positioned to discover the hidden biological interactions for better prediction and diagnosis of complex diseases. In this work, we integrated ML-based models for feature selecti...

Interpreting patient-Specific risk prediction using contextual decomposition of BiLSTMs: application to children with asthma.

BMC medical informatics and decision making
BACKGROUND: Predictive modeling with longitudinal electronic health record (EHR) data offers great promise for accelerating personalized medicine and better informs clinical decision-making. Recently, deep learning models have achieved state-of-the-a...

A comparative study of machine learning classifiers for risk prediction of asthma disease.

Photodiagnosis and photodynamic therapy
Asthma is a chronic disease characterized by wheezing, chest tightening and difficulty in breathing due to inflammation of lung airways. Early risk prediction of asthma is crucial for proper and effective management. This study presents the use of ma...

Prodromal clinical, demographic, and socio-ecological correlates of asthma in adults: a 10-year statewide big data multi-domain analysis.

The Journal of asthma : official journal of the Association for the Care of Asthma
To identify prodromal correlates of asthma as compared to chronic obstructive pulmonary disease and allied-conditions (COPDAC) using a multi domain analysis of socio-ecological, clinical, and demographic domains. This is a retrospective case-risk-co...

Predicting asthma attacks in primary care: protocol for developing a machine learning-based prediction model.

BMJ open
INTRODUCTION: Asthma is a long-term condition with rapid onset worsening of symptoms ('attacks') which can be unpredictable and may prove fatal. Models predicting asthma attacks require high sensitivity to minimise mortality risk, and high specificit...