AIMC Topic: Automation, Laboratory
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Establishment of low-cost laboratory automation processes using AutoIt and 4-axis robots.
SLAS technology
Jul 10, 2022
In most small laboratories, many processes are not yet automated because existing laboratory automation solutions are usually expensive and inflexible to use. Examples of this are autosamplers that are only compatible with one specific laboratory ins...
Automated procedure to assess pup retrieval in laboratory mice.
Scientific reports
Jan 31, 2022
All mammalian mothers form some sort of caring bond with their infants that is crucial to the development of their offspring. The Pup Retrieval Test (PRT) is the leading procedure to assess pup-directed maternal care in laboratory rodents, used in a ...
Combined strategy of knowledge-based rule selection and historical data percentile-based range determination to improve an autoverification system for clinical chemistry test results.
Journal of clinical laboratory analysis
Jan 10, 2022
BACKGROUND: Current autoverification, which is only knowledge-based, has low efficiency. Regular historical data analysis may improve autoverification range determination. We attempted to enhance autoverification by selecting autoverification rules b...
Towards robotic laboratory automation Plug & Play: The "LAPP" framework.
SLAS technology
Dec 7, 2021
Increasing the level of automation in pharmaceutical laboratories and production facilities plays a crucial role in delivering medicine to patients. However, the particular requirements of this field make it challenging to adapt cutting-edge technolo...
Automating cell counting in fluorescent microscopy through deep learning with c-ResUnet.
Scientific reports
Nov 25, 2021
Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are generally easy t...
Quick Annotator: an open-source digital pathology based rapid image annotation tool.
The journal of pathology. Clinical research
Jul 19, 2021
Image-based biomarker discovery typically requires accurate segmentation of histologic structures (e.g. cell nuclei, tubules, and epithelial regions) in digital pathology whole slide images (WSIs). Unfortunately, annotating each structure of interest...
Can AI-assisted microscope facilitate breast HER2 interpretation? A multi-institutional ring study.
Virchows Archiv : an international journal of pathology
Jul 19, 2021
The level of human epidermal growth factor receptor-2 (HER2) protein and gene expression in breast cancer is an essential factor in judging the prognosis of breast cancer patients. Several investigations have shown high intraobserver and interobserve...
Humans
Artificial Intelligence
Female
Reproducibility of Results
Automation, Laboratory
Retrospective Studies
Image Interpretation, Computer-Assisted
Predictive Value of Tests
Observer Variation
Breast Neoplasms
Receptor, ErbB-2
Microscopy
Immunohistochemistry
Biomarkers, Tumor
Carcinoma, Ductal, Breast
In Situ Hybridization, Fluorescence
China
Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning.
Archives of toxicology
Jul 10, 2021
The in vitro micronucleus assay is a globally significant method for DNA damage quantification used for regulatory compound safety testing in addition to inter-individual monitoring of environmental, lifestyle and occupational factors. However, it re...
Artificial intelligence in pathology and laboratory medicine.
Journal of clinical pathology
May 24, 2021
Artificial intelligence for advance requesting of immunohistochemistry in diagnostically uncertain prostate biopsies.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
May 20, 2021
The use of immunohistochemistry in the reporting of prostate biopsies is an important adjunct when the diagnosis is not definite on haematoxylin and eosin (H&E) morphology alone. The process is however inherently inefficient with delays while waiting...
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