AI Medical Compendium Topic

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Automation, Laboratory

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Automating a Magnetic 3D Spheroid Model Technology for High-Throughput Screening.

SLAS technology
Affordable and physiologically relevant three-dimensional (3D) cell-based assays used in high-throughput screening (HTS) are on the rise in early drug discovery. These technologies have been aided by the recent adaptation of novel microplate treatmen...

Automated System for Small-Population Single-Particle Processing Enabled by Exclusive Liquid Repellency.

SLAS technology
Exclusive liquid repellency (ELR) describes an extreme wettability phenomenon in which a liquid phase droplet is completely repelled from a solid phase when exposed to a secondary immiscible liquid phase. Earlier, we developed a multi-liquid-phase op...

A Laboratory-Built Fully Automated Ultrasonication Robot for Filamentous Fungi Homogenization.

SLAS technology
This article presents the design and development of a new hands-free ultrasonication robot for filamentous fungi homogenization. The platform was constructed with a modified inexpensive 3D printer, equipped with an upward-facing camera, a custom-desi...

Integrated Robotic Mini Bioreactor Platform for Automated, Parallel Microbial Cultivation With Online Data Handling and Process Control.

SLAS technology
During process development, the experimental search space is defined by the number of experiments that can be performed in specific time frames but also by its sophistication (e.g., inputs, sensors, sampling frequency, analytics). High-throughput liq...

An automated 3D modeling pipeline for constructing 3D models of MONOGENEAN HARDPART using machine learning techniques.

BMC bioinformatics
BACKGROUND: Studying structural and functional morphology of small organisms such as monogenean, is difficult due to the lack of visualization in three dimensions. One possible way to resolve this visualization issue is to create digital 3D models wh...

Automated identification of Myxobacterial genera using Convolutional Neural Network.

Scientific reports
The Myxococcales order consist of eleven families comprising30 genera, and are featured by the formation of the highest level of differential structure aggregations called fruiting bodies. These multicellular structures are essential for their resist...

Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study.

The Lancet. Oncology
BACKGROUND: The Gleason score is the strongest correlating predictor of recurrence for prostate cancer, but has substantial inter-observer variability, limiting its usefulness for individual patients. Specialised urological pathologists have greater ...

Robotic automation of a UHPLC/MS-MS method profiling one-carbon metabolites, amino acids, and precursors in plasma.

Analytical biochemistry
Amino acids (AAs) and one-carbon (1-C) metabolism compounds are involved in a range of key metabolic pathways, and mediate numerous health and disease processes in the human body. Previous assays have quantified a limited selection of these compounds...

Image analysis and artificial intelligence in infectious disease diagnostics.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
BACKGROUND: Microbiologists are valued for their time-honed skills in image analysis, including identification of pathogens and inflammatory context in Gram stains, ova and parasite preparations, blood smears and histopathologic slides. They also mus...