AIMC Topic: Bacteria
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Responses of Microbial Community to Heterogeneous Dissolved Organic Nitrogen Constituents in the Hyporheic Zones of Treated Sewage-Dominated Rivers.
Microbial ecology
Jul 2, 2025
The hyporheic zone (HZ) of treated sewage-dominated rivers serves as a critical biogeochemical hotspot for dissolved organic nitrogen (DON) transformation, yet the mechanisms linking DON chemodiversity to microbial community dynamics remain poorly re...
Unveiling the role of microbial rease in ureolysis-induced calcium carbonate precipitation, Its mechanistic insights, and emerging applications.
World journal of microbiology & biotechnology
Jun 25, 2025
Urease (urea amidohydrolase, EC 3.5.1.5) is a metalloenzyme that catalyzes the hydrolysis of urea into ammonia and carbamate, playing a pivotal role in numerous biotechnological applications. Initially sourced from plants (such as Canavalia ensiformi...
Mucosal immune responses and intestinal microbiome associations in wild spotted hyenas (Crocuta crocuta).
Communications biology
Jun 13, 2025
Little is known about host-gut microbiome interactions within natural populations at the intestinal mucosa, the primary interface. We investigate associations between the intestinal microbiome and mucosal immune measures while controlling for host, s...
Gut microbiota alterations are linked to COVID-19 severity in North African and European populations.
NPJ biofilms and microbiomes
Jun 13, 2025
Although COVID-19 primarily affects the respiratory system, many patients experience gastrointestinal symptoms, suggesting a role for the gut microbiota in disease pathogenesis. To explore this, we performed shotgun metagenomic sequencing on stool sa...
Fecal gut microbiota and amino acids as noninvasive diagnostic biomarkers of Pediatric inflammatory bowel disease.
Gut microbes
Jun 12, 2025
BACKGROUND AND AIMS: Fecal calprotectin (FCP) has limited specificity as diagnostic biomarker of pediatric inflammatory bowel disease (IBD), leading to unnecessary invasive endoscopies. This study aimed to develop and validate a fecal microbiota and ...
Machine learning based gut microbiota pattern and response to fiber as a diagnostic tool for chronic inflammatory diseases.
BMC microbiology
Jun 6, 2025
Gut microbiota has been implicated in the pathogenesis of multiple gastrointestinal (GI) and systemic metabolic and inflammatory disorders where disrupted gut microbiota composition and function (dysbiosis) has been found in multiple studies. Thus, h...
A descriptor-free machine learning framework to improve antigen discovery for bacterial pathogens.
PloS one
Jun 5, 2025
Identifying protective antigens (PAs), i.e., targets for bacterial vaccines, is challenging as conducting in-vivo tests at the proteome scale is impractical. Reverse Vaccinology (RV) aids in narrowing down the pool of candidates through computational...
AI-Driven Antimicrobial Peptide Discovery: Mining and Generation.
Accounts of chemical research
Jun 3, 2025
ConspectusThe escalating threat of antimicrobial resistance (AMR) poses a significant global health crisis, potentially surpassing cancer as a leading cause of death by 2050. Traditional antibiotic discovery methods have not kept pace with the rapidl...
Impact of microbial profile integration on machine learning predictions of methane production: synergies and trade-offs with physicochemical parameters.
Bioresource technology
Jun 1, 2025
Microbial sequencing data were rarely integrated into the prediction of methane production using machine learning (ML) models because of high dimensionality and the lack of a systematic way to evaluate the change of insight gained from modelling with...
Single-tooth resolved, whole-mouth prediction of early childhood caries via spatiotemporal variations of plaque microbiota.
Cell host & microbe
May 30, 2025
Early childhood caries (ECC) exhibits tooth specificity, highlighting the need for single-tooth-level prevention. We profiled 2,504 dental plaque microbiota samples from 89 preschoolers across two cohorts, tracking compositional changes with imputed ...
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