AIMC Topic: Bacterial Physiological Phenomena

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The bacterial interlocked process ONtology (BiPON): a systemic multi-scale unified representation of biological processes in prokaryotes.

Journal of biomedical semantics
BACKGROUND: High-throughput technologies produce huge amounts of heterogeneous biological data at all cellular levels. Structuring these data together with biological knowledge is a critical issue in biology and requires integrative tools and methods...

Mapping quorum sensing onto neural networks to understand collective decision making in heterogeneous microbial communities.

Physical biology
Microbial communities frequently communicate via quorum sensing (QS), where cells produce, secrete, and respond to a threshold level of an autoinducer (AI) molecule, thereby modulating gene expression. However, the biology of QS remains incompletely ...

A synthetic multi-cellular network of coupled self-sustained oscillators.

PloS one
Engineering artificial networks from modular components is a major challenge in synthetic biology. In the past years, single units, such as switches and oscillators, were successfully constructed and implemented. The effective integration of these pa...

Spatial dispersal of bacterial colonies induces a dynamical transition from local to global quorum sensing.

Physical review. E
Bacteria communicate using external chemical signals called autoinducers (AI) in a process known as quorum sensing (QS). QS efficiency is reduced by both limitations of AI diffusion and potential interference from neighboring strains. There is thus a...

Two-Swim Operators in the Modified Bacterial Foraging Algorithm for the Optimal Synthesis of Four-Bar Mechanisms.

Computational intelligence and neuroscience
This paper presents two-swim operators to be added to the chemotaxis process of the modified bacterial foraging optimization algorithm to solve three instances of the synthesis of four-bar planar mechanisms. One swim favors exploration while the seco...

Development of an automatic identification algorithm for antibiogram analysis.

Computers in biology and medicine
Routinely, diagnostic and microbiology laboratories perform antibiogram analysis which can present some difficulties leading to misreadings and intra and inter-reader deviations. An Automatic Identification Algorithm (AIA) has been proposed as a solu...

Machine learning assisted design of highly active peptides for drug discovery.

PLoS computational biology
The discovery of peptides possessing high biological activity is very challenging due to the enormous diversity for which only a minority have the desired properties. To lower cost and reduce the time to obtain promising peptides, machine learning ap...

Confined swimming of bio-inspired microrobots in rectangular channels.

Bioinspiration & biomimetics
Controlled swimming of bio-inspired microrobots in confined spaces needs to be understood well for potential use in medical applications in conduits and vessels inside the body. In this study, experimental and computational studies are performed for ...

A Fresh Shine onCystic Fibrosis Inhalation Therapy: Antimicrobial Synergy of Polymyxin B in Combination with Silver Nanoparticles.

Journal of biomedical nanotechnology
This in vitro study aimed to investigate the synergistic antibacterial activity of polymyxin B in combination with 2 nm silver nanoparticles (NPs) against Gram-negative pathogens commonly isolated from the cystic fibrosis (CF) lung. The in vitro syne...