AIMC Topic: Biocompatible Materials

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Hybrid additive manufacturing and data-guided design optimization for graded anterior cruciate ligament engineering.

Biomedical materials (Bristol, England)
Interface tissues, such as the enthesis connecting ligaments to bone, present multiphasic architectures with continuous gradients in structure, composition, and mechanics. Engineering such complex transitions remains a major challenge in biofabricati...

Machine Learning for the Prediction of Size and Encapsulation Efficiency of mRNA-Loaded Lipid Nanoparticles Following a Postencapsulation Approach.

ACS applied bio materials
Lipid nanoparticles (LNPs) have gained significant attention thanks to their ability to encapsulate and deliver mRNA. Exploring a variety of lipid compositions and different preparation processes is essential for a better understanding of the mRNA en...

Artificial intelligence-enabled hydrogels: innovations and applications.

Journal of materials chemistry. B
Due to the excellent biocompatibility and adjustability, hydrogels have broadened their application in different fields, such as 3D printing, tissue engineering, drug delivery, and biosensing. However, traditional hydrogel research is confronted with...

Targeting Ischemic Stroke with Neural Stem Cells: Insights into Endogenous Repair Mechanisms, Biomaterial-Based Delivery, and Exosome Therapies.

Molecular neurobiology
Neurological diseases, such as stroke, are typically deemed refractory because of the adult mammalian brain's poor ability to self-repair and regenerate, resulting in irreparable cellular damage. Neural stem cells (NSCs) have distinct capabilities to...

Hydrogel-based sensors for multimodal health monitoring: from material design to intelligent sensing.

Nanoscale
Hydrogels, due to their biocompatibility, tunability, and stimulus responsiveness, are promising materials for flexible health monitoring. However, traditional hydrogel sensors suffer from various limitations in terms of long-term stability, signal f...

Functional biomaterials and machine learning approaches for phenotyping heterogeneous tumor cells and extracellular vesicles.

Biomaterials science
Heterogeneity in cancer is known to be a contributor to the formation of metastatic lesions, poor prognosis, and ultimately undermines therapeutic efficacy. This same tumor heterogeneity is reflected in circulating tumor cells (CTCs) and tumor derive...

Comparative investigation into flexible alginate-based hydrogel sponges with excellent biocompatibility and breathability for reliable strain and pressure sensors.

Mikrochimica acta
Flexible sensors with a porous hydrogel structure have attracted enormous attention for their extensive potential prospects in the fields of wearable electronics and human-machine interaction (HMI). Nevertheless, these sensors encounter significant c...

Laser-induced graphene for biomedical applications: innovations in health monitoring and diagnostics.

Nanoscale horizons
Laser-induced graphene (LIG) has emerged as a versatile and sustainable nanomaterial for biomedical applications, offering a unique combination of tunable surface chemistry, high electrical conductivity, mechanical flexibility, and biocompatibility. ...

Intelligent microstructure materials for diagnosis and treatment of osteoarthritis: progress and AI-enpowered future.

Bone research
Osteoarthritis (OA) is a widespread joint disorder that has emerged as a significant global healthcare challenge. Over the past decade, advancements in material science and medicine have transformed the development of functional materials aimed at ad...

Alginate-based 3D bioprinting strategies for structure-function integrated tissue regeneration.

Journal of materials chemistry. B
Alginate-based biomaterials have been widely used for tissue repair and regeneration, owing to their tunability, biocompatibility, biodegradability, and low cytotoxicity. With the rapid advancement of bioprinting technology, alginate has increasingly...