AIMC Topic: Biocompatible Materials

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Integrating Deep Learning and Real-Time Imaging to Visualize In Situ Self-Assembly of Self-Healing Interpenetrating Polymer Networks Formed by Protein and Polysaccharide Fibers.

ACS applied materials & interfaces
Fibrillar protein hydrogels are promising sustainable biomaterials for biomedical applications, but their practical use is often limited by insufficient mechanical strength and stability. To address these challenges, we transformed native proteins in...

Decoding tissue complexity: multiscale mapping of chemistry-structure-function relationships through advanced visualization technologies.

Journal of materials chemistry. B
Comprehensively acquiring biological tissue information is pivotal for advancing our understanding of biological systems, elucidating disease mechanisms, and developing innovative clinical strategies. Biological tissues, as nature's archetypal biomat...

Self-assembling peptide hydrogels: design, mechanisms, characterization, and biomedical applications.

Soft matter
Self-assembled peptide hydrogels have emerged as a research frontier in biomedical engineering due to their exceptional water-retention capacity and spatiotemporal drug release kinetics. Researchers can fabricate biomaterials with customizable struct...

Screening of Biomaterials for Stem Cell Culture Applications.

ACS biomaterials science & engineering
Stem cells have a considerable role to play in future biomedical breakthroughs due to their therapeutic potential. As stem cells may be studied in a variety of different applications, a "one size fits all" approach to the stem cell culture substrate ...

A soft robotic total artificial hybrid heart.

Nature communications
End-stage heart failure is a deadly disease. Current total artificial hearts (TAHs) carry high mortality and morbidity and offer low quality of life. To overcome current biocompatibility issues, we propose the concept of a soft robotic, hybrid (pumpi...

Hierarchical design of silkworm silk for functional composites.

Chemical Society reviews
Silk-reinforced composites (SRCs) manifest the unique properties of silkworm silk fibers, offering enhanced mechanical strength, biocompatibility, and biodegradability. These composites present an eco-friendly alternative to conventional synthetic ma...

Optimal structural characteristics of osteoinductivity in bioceramics derived from a novel high-throughput screening plus machine learning approach.

Biomaterials
Osteoinduction is an important feature of the next generation of bone repair materials. But the key structural factors and parameters of osteoinductive scaffolds are not yet clarified. This study leverages the efficiency of high-throughput screening ...

Surrogate modeling of electrospun PVA/PLA nanofibers using artificial neural network for biomedical applications.

Scientific reports
Blending poly (lactic acid) (PLA) with poly (vinyl alcohol) (PVA) improves the strength and hydrophilicity of nanofibers, making them suitable for biomedical applications like wound dressings. This study explores how electrospinning parameters-applie...

Ultrasound-activated piezoelectric biomaterials for cartilage regeneration.

Ultrasonics sonochemistry
Due to the low density of chondrocytes and limited ability to repair damaged extracellular matrix (ECM) in cartilage, many patients with congenital or acquired craniofacial trauma require filler graft materials to support facial structure, restore fu...

Predicting rheological properties of HAMA/GelMA hybrid hydrogels via machine learning.

Journal of the mechanical behavior of biomedical materials
- Rheological properties are pivotal in determining the printability of biomaterials, directly impacting the success of 3D bioprinted constructs. Understanding the intricate relationship between biomaterial formulations, rheological behavior and prin...