AIMC Topic: Brain Neoplasms

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Machine learning-based prediction model for brain metastasis in patients with extensive-stage small cell lung cancer.

Scientific reports
Brain metastases (BMs) in extensive-stage small cell lung cancer (ES-SCLC) are often associated with poor survival rates and quality of life, making the timely identification of high-risk patients for BMs in ES-SCLC crucial. Patients diagnosed with E...

Predicting intraoperative 5-ALA-induced tumor fluorescence via MRI and deep learning in gliomas with radiographic lower-grade characteristics.

Journal of neuro-oncology
PURPOSE: Lower-grade gliomas typically exhibit 5-aminolevulinic acid (5-ALA)-induced fluorescence in only 20-30% of cases, a rate that can be increased by doubling the administered dose of 5-ALA. Fluorescence can depict anaplastic foci, which can be ...

Using machine learning to develop a stacking ensemble learning model for the CT radiomics classification of brain metastases.

Scientific reports
The objective of this study was to explore the potential of machine-learning techniques in the automatic identification and classification of brain metastases from a radiomic perspective, aiming to improve the accuracy of tumor volume assessment for ...

Intraoperative label-free tissue diagnostics using a stimulated Raman histology imaging system with artificial intelligence: An initial experience.

Clinical neurology and neurosurgery
BACKGROUND: Accurate intraoperative tissue diagnostics could impact on decision making regarding the extent of resection (EOR) during brain tumor surgery. Stimulated Raman histology (SRH) is a label-free optical imaging method that uses different bio...

Validation of SynthSeg segmentation performance on CT using paired MRI from radiotherapy patients.

NeuroImage
INTRODUCTION: Manual segmentation of medical images is labor intensive and especially challenging for images with poor contrast or resolution. The presence of disease exacerbates this further, increasing the need for an automated solution. To this ex...

AI tool for predicting MGMT methylation in glioblastoma for clinical decision support in resource limited settings.

Scientific reports
Glioblastoma is an aggressive brain cancer with a poor prognosis. The O6-methylguanine-DNA methyltransferase (MGMT) gene methylation status is crucial for treatment stratification, yet economic constraints often limit access. This study aims to devel...

Brain tumor diagnosis in MRI scans images using Residual/Shuffle Network optimized by augmented Falcon Finch optimization.

Scientific reports
Brain tumor diagnosis is an important task in prognosing and treatment planning of the patients with brain cancer. in the meantime, using the Magnetic Resonance Imaging (MRI) as a commonly used non-invasive imaging technique provide the experts a hel...

Machine learning model reveals the role of angiogenesis and EMT genes in glioma patient prognosis and immunotherapy.

Biology direct
Gliomas represent a highly aggressive class of tumors located in the brain. Despite the availability of multiple treatment modalities, the prognosis for patients diagnosed with glioma remains unfavorable. Therefore, further exploration of new biomark...

Discovery of key molecular signatures for diagnosis and therapies of glioblastoma by combining supervised and unsupervised learning approaches.

Scientific reports
Glioblastoma (GBM) is the most malignant brain cancer and one of the leading causes of cancer-related death globally. So, identifying potential molecular signatures and associated drug molecules are crucial for diagnosis and therapies of GBM. This st...