AIMC Topic: Brain

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Impaired interhemispheric synchrony in patients with iridocyclitis and classification using machine learning: an fMRI study.

Frontiers in immunology
BACKGROUND: This study examined the interhemispheric integration function pattern in patients with iridocyclitis utilizing the voxel-mirrored homotopic connectivity (VMHC) technique. Additionally, we investigated the ability of VMHC results to distin...

Automatic Segmentation of Sylvian Fissure in Brain Ultrasound Images of Pre-Term Infants Using Deep Learning Models.

Ultrasound in medicine & biology
OBJECTIVE: Segmentation of brain sulci in pre-term infants is crucial for monitoring their development. While magnetic resonance imaging has been used for this purpose, cranial ultrasound (cUS) is the primary imaging technique used in clinical practi...

Conditional generative diffusion deep learning for accelerated diffusion tensor and kurtosis imaging.

Magnetic resonance imaging
PURPOSE: The purpose of this study was to develop DiffDL, a generative diffusion probabilistic model designed to produce high-quality diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) metrics from a reduced set of diffusion-weighted...

A Context-Dependent CNN-Based Framework for Multiple Sclerosis Segmentation in MRI.

International journal of neural systems
Despite several automated strategies for identification/segmentation of Multiple Sclerosis (MS) lesions in Magnetic Resonance Imaging (MRI) being developed, they consistently fall short when compared to the performance of human experts. This emphasiz...

Adapting to time: Why nature may have evolved a diverse set of neurons.

PLoS computational biology
Brains have evolved diverse neurons with varying morphologies and dynamics that impact temporal information processing. In contrast, most neural network models use homogeneous units that vary only in spatial parameters (weights and biases). To explor...

Neural networks with optimized single-neuron adaptation uncover biologically plausible regularization.

PLoS computational biology
Neurons in the brain have rich and adaptive input-output properties. Features such as heterogeneous f-I curves and spike frequency adaptation are known to place single neurons in optimal coding regimes when facing changing stimuli. Yet, it is still u...

A machine learning approach for identifying anatomical biomarkers of early mild cognitive impairment.

PeerJ
BACKGROUND: Alzheimer's Disease (AD) poses a major challenge as a neurodegenerative disorder, and early detection is critical for effective intervention. Magnetic resonance imaging (MRI) is a critical tool in AD research due to its availability and c...

Contrastive machine learning reveals species -shared and -specific brain functional architecture.

Medical image analysis
A deep comparative analysis of brain functional connectome across species in primates has the potential to yield valuable insights for both scientific and clinical applications. However, the interspecies commonality and differences are inherently ent...

Time-Frequency functional connectivity alterations in Alzheimer's disease and frontotemporal dementia: An EEG analysis using machine learning.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVE: Alzheimer's disease (AD) and frontotemporal dementia (FTD) are prevalent neurodegenerative diseases characterized by altered brain functional connectivity (FC), affecting over 100 million people worldwide. This study aims to identify disti...

Where, why, and how is bias learned in medical image analysis models? A study of bias encoding within convolutional networks using synthetic data.

EBioMedicine
BACKGROUND: Understanding the mechanisms of algorithmic bias is highly challenging due to the complexity and uncertainty of how various unknown sources of bias impact deep learning models trained with medical images. This study aims to bridge this kn...