AIMC Topic: Chromatography, High Pressure Liquid

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Optimal extraction bioactive components of tetramethylpyrazine in Chinese herbal medicine jointly using back propagation neural network and genetic algorithm in R language.

Pakistan journal of pharmaceutical sciences
A combinational approach of back propagation neural network (BPNN) and genetic algorithm (GA) was proposed in the present study to optimize the extraction technology of tetramethylpyrazine (TMP) in Ligusticum wallichii Franchat. Based on the single f...

Absorption and biotransformation of four compounds in the Guizhi decoction in the gastrointestinal tracts of rats.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
OBJECTIVE: To study the absorption and biotransformation of liquiritin, cinnamic acid, paeoniflorin, and glycyrrhizic acid in the Guizhi decoction (GZD) in the gastrointestinal tracts of rats.

Ultrashort ssDNA in Retinoblastoma Patients Blood Plasma Detected by a Novel High Resolution HPLC Technique: a Preliminary Report.

Acta medica (Hradec Kralove)
A significant population of ultrashort (50-150n) single-stranded DNA fragments were found in exosome-free blood plasma of retinoblastoma patients (6.84 ng mL-1), but not in plasma of healthy donors. An original high resolution HPLC technique has been...

Reverse-Phase Chromatographic Determination and Intrinsic Stability Behavior of 5-[(4-Chlorophenoxy)Methyl]-1,3,4-Oxadiazole-2-Thiol.

Acta pharmaceutica (Zagreb, Croatia)
The study describes the development and preliminary validation of a simple reverse-phase chromatographic method for determination of a novel drug candidate, 5-[(4-chlorophenoxy) methyl]-1,3,4-oxadiazole-2-thiol (OXCPM), in bulk and stressed solution,...

Stability of 90 mg/mL cefuroxime sodium solution for administration by continuous infusion.

Journal of chemotherapy (Florence, Italy)
Continuous infusions of β-lactam antibiotics increase pharmacokinetic/pharmacodynamic target attainment. However, this way of administration brings about some practical issues such as stability. This study aims to determine the stability of a 90 mg/m...

[Determination of total phthalates in perfume and their exposure assessment].

Se pu = Chinese journal of chromatography
A novel method for rapid screening of phthalates (PAEs) in perfumes was developed. The PAEs were hydrolyzed to phthalic acid (PA), and the PA in the acidified solution was extracted with tributyl phosphate (TBP) which was detected by high performance...

[Determination of eight components in Lamiophlomis rotate by UPLC method and preliminary study on influencing factors of contents].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
To establish a method for simultaneous determination of the contents of sesamoside, menthyl chloride, chlorogenic acid, caffeic acid, 8-O-acetyl-phloridzin methyl ester, forsythiaside B, luteolin, and ergosterol, the LIPLC analysis was performed on a...

Development and validation of a LC-FL method for the simultaneous determination of doxorubicin and celecoxib in nanoparticulate fixed dose combination (NanoFDC).

Die Pharmazie
An isocratic reversed phase HPLC method for the simultaneous determination of doxorubicine (DOX) and celecoxib (CXB) out of a nanoparticulate fixed dose combination (NanoFDC) was developed and validated. Linearity of the results was demonstrated from...

[Determination of 4 kinds of plant growth regulator in bean sprout by solid phase extraction column coupled with ultra-high performance liquid chromatography].

Wei sheng yan jiu = Journal of hygiene research
OBJECTIVE: A method for the determination of 6-benzylaminopurine( 6-BAP), isopentennyladenine( z-IP), 4-fluorophenoxyacetic acid( 4-FPA), 4-chlorophenoxyacetic acid( 4-CPA) in bean sprout was developed using solid phase extraction column with ultra-h...

[Determination of polycyclic aromatic hydrocarbons in girls and association between polycyclic aromatic hydrocarbons exposure and puberty timing].

Wei sheng yan jiu = Journal of hygiene research
OBJECTIVE: To develop amethod for simultaneous determination of four metabolites of polycyclic aromatic hydrocarbons( PAHs), and to study the association between puberty timing of girls and PAHs exposure levels in Chongqing.