AIMC Topic: Clinical Trials as Topic

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Demystifying AI in healthcare.

BMJ (Clinical research ed.) Sep 9, 2020
Humans Delivery of Health Care Clinical Trials as Topic Artificial Intelligence Research Design
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Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI Extension.

BMJ (Clinical research ed.) Sep 9, 2020
The SPIRIT 2013 (The Standard Protocol Items: Recommendations for Interventional Trials) statement aims to improve the completeness of clinical trial protocol reporting, by providing evidence-based recommendations for the minimum set of items to be a...
Checklist Humans Clinical Trials as Topic Clinical Protocols Artificial Intelligence Research Design Consensus
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Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension.

Nature medicine Sep 9, 2020
The SPIRIT 2013 statement aims to improve the completeness of clinical trial protocol reporting by providing evidence-based recommendations for the minimum set of items to be addressed. This guidance has been instrumental in promoting transparent eva...
Research Design Clinical Trials as Topic Humans Artificial Intelligence
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A novel CNN algorithm for pathological complete response prediction using an I-SPY TRIAL breast MRI database.

Magnetic resonance imaging Sep 2, 2020
PURPOSE: To apply our convolutional neural network (CNN) algorithm to predict neoadjuvant chemotherapy (NAC) response using the I-SPY TRIAL breast MRI dataset.
Retrospective Studies Female Breast Neoplasms Magnetic Resonance Imaging Humans Area Under Curve Neural Networks, Computer Clinical Trials as Topic Databases, Factual Image Processing, Computer-Assisted Treatment Outcome Neoadjuvant Therapy
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Functional cardiac CT-Going beyond Anatomical Evaluation of Coronary Artery Disease with Cine CT, CT-FFR, CT Perfusion and Machine Learning.

The British journal of radiology Aug 12, 2020
The aim of this review is to provide an overview of different functional cardiac CT techniques which can be used to supplement assessment of the coronary arteries to establish the significance of coronary artery stenoses. We focus on cine-CT, CT-FFR,...
Computed Tomography Angiography Myocardial Perfusion Imaging Coronary Stenosis Clinical Trials as Topic Vascular Calcification Fractional Flow Reserve, Myocardial Machine Learning Tomography, X-Ray Computed Ventricular Function, Left Stroke Volume Coronary Angiography Coronary Artery Disease Humans
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Use of deep learning methods to translate drug-induced gene expression changes from rat to human primary hepatocytes.

PloS one Aug 11, 2020
In clinical trials, animal and cell line models are often used to evaluate the potential toxic effects of a novel compound or candidate drug before progressing to human trials. However, relating the results of animal and in vitro model exposures to r...
Deep Learning Humans Gene Expression Regulation Machine Learning Rats Neural Networks, Computer Clinical Trials as Topic Algorithms Hepatocytes Animals
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BIOINTMED: integrated biomedical knowledge base with ontologies and clinical trials.

Medical & biological engineering & computing Jul 24, 2020
Biomedical data are complex and heterogeneous. An ample reliable quantity of data is important for understanding and exploring the domain. The work aims to integrate biomedical data from various heterogeneous sources like dictionaries or corpus and a...
Databases, Pharmaceutical Toxicogenetics Clinical Trials as Topic Databases, Chemical Models, Statistical Databases, Protein Drug Interactions Drug-Related Side Effects and Adverse Reactions Knowledge Bases Humans Biological Ontologies
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Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology Jun 12, 2020
Bipolar disorder (BD) is a major healthcare and socio-economic challenge. Despite its substantial burden on society, the research activity in BD is much smaller than its economic impact appears to demand. There is a consensus that the accurate identi...
Big Data Bipolar Disorder Treatment Outcome Machine Learning Translational Research, Biomedical Global Health Humans Clinical Trials as Topic
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Robotic assistance for people with dementia: a viable option for the future?

Expert review of medical devices Jun 8, 2020
INTRODUCTION: Demographic changes in society and fewer personnel working in healthcare services have resulted in an increase in the speed of development of safe, reliable robotic assistance technologies for patients with neurological diseases. This p...
Clinical Trials as Topic Artificial Intelligence Dementia Robotics Humans
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Applying cascaded convolutional neural network design further enhances automatic scoring of arthritis disease activity on ultrasound images from rheumatoid arthritis patients.

Annals of the rheumatic diseases Jun 5, 2020
OBJECTIVES: We have previously shown that neural network technology can be used for scoring arthritis disease activity in ultrasound images from rheumatoid arthritis (RA) patients, giving scores according to the EULAR-OMERACT grading system. We have ...
Adult Male Middle Aged Severity of Illness Index Ultrasonography Arthritis, Rheumatoid Neural Networks, Computer Female Reproducibility of Results Humans Rheumatology Synovitis Image Interpretation, Computer-Assisted Clinical Trials as Topic Joints
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