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Clinical Trials as Topic

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BIOINTMED: integrated biomedical knowledge base with ontologies and clinical trials.

Medical & biological engineering & computing
Biomedical data are complex and heterogeneous. An ample reliable quantity of data is important for understanding and exploring the domain. The work aims to integrate biomedical data from various heterogeneous sources like dictionaries or corpus and a...

Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
Bipolar disorder (BD) is a major healthcare and socio-economic challenge. Despite its substantial burden on society, the research activity in BD is much smaller than its economic impact appears to demand. There is a consensus that the accurate identi...

Robotic assistance for people with dementia: a viable option for the future?

Expert review of medical devices
INTRODUCTION: Demographic changes in society and fewer personnel working in healthcare services have resulted in an increase in the speed of development of safe, reliable robotic assistance technologies for patients with neurological diseases. This p...

Applying cascaded convolutional neural network design further enhances automatic scoring of arthritis disease activity on ultrasound images from rheumatoid arthritis patients.

Annals of the rheumatic diseases
OBJECTIVES: We have previously shown that neural network technology can be used for scoring arthritis disease activity in ultrasound images from rheumatoid arthritis (RA) patients, giving scores according to the EULAR-OMERACT grading system. We have ...

Assessing the Scope and Predictors of Intentional Dose Non-adherence in Clinical Trials.

Therapeutic innovation & regulatory science
BACKGROUND: Although there is broad agreement that the accurate estimation of non-adherence rates in clinical trials is essential to determining the dose-response relationship, treatment safety and efficacy effects, no accurate estimates have ever be...

Automated quantification and architectural pattern detection of hepatic fibrosis in NAFLD.

Annals of diagnostic pathology
Accurate detection and quantification of hepatic fibrosis remain essential for assessing the severity of non-alcoholic fatty liver disease (NAFLD) and its response to therapy in clinical practice and research studies. Our aim was to develop an integr...

Oncology Research: Clinical Trial Management Systems, Electronic Medical Record, and Artificial Intelligence.

Seminars in oncology nursing
OBJECTIVE: To discuss the implications of electronic systems and regulations regarding the use of electronic systems implemented during the conduct of a clinical trial and identify the impact of such platforms on oncology nurses' responsible for prov...

Natural Language Processing for Mimicking Clinical Trial Recruitment in Critical Care: A Semi-Automated Simulation Based on the LeoPARDS Trial.

IEEE journal of biomedical and health informatics
Clinical trials often fail to recruit an adequate number of appropriate patients. Identifying eligible trial participants is resource-intensive when relying on manual review of clinical notes, particularly in critical care settings where the time win...

Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology?

Clinical pharmacology and therapeutics
As the field of artificial intelligence and machine learning (AI/ML) for drug discovery is rapidly advancing, we address the question "What is the impact of recent AI/ML trends in the area of Clinical Pharmacology?" We address difficulties and AI/ML ...