AIMC Topic: Clinical Trials as Topic

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Network science in clinical trials: A patient-centered approach.

Seminars in cancer biology
There has been a paradigm shift in translational oncology with the advent of novel molecular diagnostic tools in the clinic. However, several challenges are associated with the integration of these sophisticated tools into clinical oncology and daily...

Artificial Intelligence in Medical Practice: The Question to the Answer?

The American journal of medicine
Computer science advances and ultra-fast computing speeds find artificial intelligence (AI) broadly benefitting modern society-forecasting weather, recognizing faces, detecting fraud, and deciphering genomics. AI's future role in medical practice rem...

Text Mining of the Electronic Health Record: An Information Extraction Approach for Automated Identification and Subphenotyping of HFpEF Patients for Clinical Trials.

Journal of cardiovascular translational research
Precision medicine requires clinical trials that are able to efficiently enroll subtypes of patients in whom targeted therapies can be tested. To reduce the large amount of time spent screening, identifying, and recruiting patients with specific subt...

CATTLE (CAncer treatment treasury with linked evidence): An integrated knowledge base for personalized oncology research and practice.

CPT: pharmacometrics & systems pharmacology
Despite the existence of various databases cataloging cancer drugs, there is an emerging need to support the development and application of personalized therapies, where an integrated understanding of the clinical factors and drug mechanism of action...

Automatic data source identification for clinical trial eligibility criteria resolution.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Clinical trial coordinators refer to both structured and unstructured sources of data when evaluating a subject for eligibility. While some eligibility criteria can be resolved using structured data, some require manual review of clinical notes. An i...

Nasal Dilators (Breathe Right Strips and NoZovent) for Snoring and OSA: A Systematic Review and Meta-Analysis.

Pulmonary medicine
. To systematically review the international literature for studies evaluating internal (NoZovent) and external (Breathe Right Strips) nasal dilators as treatment for obstructive sleep apnea (OSA). . Systematic review with meta-analysis. . Four datab...

Learning disease relationships from clinical drug trials.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Our objective is to test the limits of the assumption that better learning from data in medicine requires more granular data. We hypothesize that clinical trial metadata contains latent scientific, clinical, and regulatory expert knowledge...

Will they participate? Predicting patients' response to clinical trial invitations in a pediatric emergency department.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: (1) To develop an automated algorithm to predict a patient's response (ie, if the patient agrees or declines) before he/she is approached for a clinical trial invitation; (2) to assess the algorithm performance and the predictors on real-w...

Bilateral robots for upper-limb stroke rehabilitation: State of the art and future prospects.

Medical engineering & physics
Robot-assisted bilateral upper-limb training grows abundantly for stroke rehabilitation in recent years and an increasing number of devices and robots have been developed. This paper aims to provide a systematic overview and evaluation of existing bi...