Recent advances have given rise to a spectrum of digital health technologies that have the potential to revolutionize the design and conduct of cardiovascular clinical trials. Advances in domain tasks such as automated diagnosis and classification, s...
Approaches to artificial intelligence and machine learning (AI/ML) continue to advance in the field of drug development. A sound understanding of the underlying concepts and guiding principles of AI/ML implementation is a prerequisite to identifying ...
Artificial intelligence (AI) is making a significant impact across various industries, including healthcare, where it is driving innovation and increasing efficiency. In the fields of Quantitative Clinical Pharmacology (QCP) and Translational Science...
Journal of the American Medical Informatics Association : JAMIA
Mar 1, 2025
OBJECTIVE: Extracting PICO elements-Participants, Intervention, Comparison, and Outcomes-from clinical trial literature is essential for clinical evidence retrieval, appraisal, and synthesis. Existing approaches do not distinguish the attributes of P...
Journal of the American Medical Informatics Association : JAMIA
Mar 1, 2025
OBJECTIVES: Clinical trials (CTs) are essential for improving patient care by evaluating new treatments' safety and efficacy. A key component in CT protocols is the study population defined by the eligibility criteria. This study aims to evaluate the...
Journal of the American College of Cardiology
Nov 12, 2024
Randomized clinical trials are the gold standard for establishing the efficacy and safety of cardiovascular therapies. However, current pivotal trials are expensive, lengthy, and insufficiently diverse. Emerging artificial intelligence (AI) technolog...
Journal of the American Medical Informatics Association : JAMIA
Nov 1, 2024
OBJECTIVE: The objective of our research is to conduct a comprehensive review that aims to systematically map, describe, and summarize the current utilization of artificial intelligence (AI) in the recruitment and retention of participants in clinica...
Studies in health technology and informatics
Aug 22, 2024
We present an NLP web-based tool to help users understand consent forms (CFs) and clinical trial announcements (CTAs) in Spanish. For complex word identification, we collected: 1) a lexicon of technical terms and simplified synonyms (14 465 entries);...
Translational vision science & technology
Aug 1, 2024
PURPOSE: To explore the contributions of fundus autofluorescence (FAF) topographic imaging features to the performance of convolutional neural network-based deep learning (DL) algorithms in predicting geographic atrophy (GA) growth rate.