AIMC Topic: Clinical Trials as Topic

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A Deep-Learning Algorithm to Predict Short-Term Progression to Geographic Atrophy on Spectral-Domain Optical Coherence Tomography.

JAMA ophthalmology
IMPORTANCE: The identification of patients at risk of progressing from intermediate age-related macular degeneration (iAMD) to geographic atrophy (GA) is essential for clinical trials aimed at preventing disease progression. DeepGAze is a fully autom...

Integrating Artificial Intelligence and Machine Learning Into Cancer Clinical Trials.

Seminars in radiation oncology
The practice of oncology requires analyzing and synthesizing abundant data. From the patient's workup to determine eligibility to the therapies received to the post-treatment surveillance, practitioners must constantly juggle, evaluate, and weigh dec...

Automated Matching of Patients to Clinical Trials: A Patient-Centric Natural Language Processing Approach for Pediatric Leukemia.

JCO clinical cancer informatics
PURPOSE: Matching patients to clinical trials is cumbersome and costly. Attempts have been made to automate the matching process; however, most have used a trial-centric approach, which focuses on a single trial. In this study, we developed a patient...

NLP-Assisted Pipeline for COVID-19 Core Outcome Set Identification Using ClinicalTrials.gov.

Studies in health technology and informatics
Core outcome sets (COS) are necessary to ensure the systematic collection, metadata analysis and sharing the information across studies. However, development of an area-specific clinical research is costly and time consuming. ClinicalTrials.gov, as a...

A web-based tool for automatically linking clinical trials to their publications.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Evidence synthesis teams, physicians, policy makers, and patients and their families all have an interest in following the outcomes of clinical trials and would benefit from being able to evaluate both the results posted in trial registrie...

Gender-sensitive word embeddings for healthcare.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: To analyze gender bias in clinical trials, to design an algorithm that mitigates the effects of biases of gender representation on natural-language (NLP) systems trained on text drawn from clinical trials, and to evaluate its performance.

An Evaluation of Pretrained BERT Models for Comparing Semantic Similarity Across Unstructured Clinical Trial Texts.

Studies in health technology and informatics
Processing unstructured clinical texts is often necessary to support certain tasks in biomedicine, such as matching patients to clinical trials. Among other methods, domain-specific language models have been built to utilize free-text information. Th...