AIMC Topic: Clinical Trials as Topic
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CPRS: a clinical protocol recommendation system based on LLMs.
International journal of medical informatics
Dec 4, 2024
BACKGROUND: As fundamental documents in clinical trials, clinical trial protocols are intended to ensure that trials are conducted according to the objectives set by researchers. The advent of large models with superior semantic performance compared ...
Structural analysis and intelligent classification of clinical trial eligibility criteria based on deep learning and medical text mining.
Journal of biomedical informatics
Nov 26, 2024
OBJECTIVE: To enhance the efficiency, quality, and innovation capability of clinical trials, this paper introduces a novel model called CTEC-AC (Clinical Trial Eligibility Criteria Automatic Classification), aimed at structuring clinical trial eligib...
Natural Language Processing to Adjudicate Heart Failure Hospitalizations in Global Clinical Trials.
Circulation. Heart failure
Nov 16, 2024
BACKGROUND: Medical record review by a physician clinical events committee is the gold standard for identifying cardiovascular outcomes in clinical trials, but is labor-intensive and poorly reproducible. Automated outcome adjudication by artificial i...
Learning to match patients to clinical trials using large language models.
Journal of biomedical informatics
Oct 9, 2024
OBJECTIVE: This study investigates the use of Large Language Models (LLMs) for matching patients to clinical trials (CTs) within an information retrieval pipeline. Our objective is to enhance the process of patient-trial matching by leveraging the se...
How can quantum computing be applied in clinical trial design and optimization?
Trends in pharmacological sciences
Sep 23, 2024
Clinical trials are necessary for assessing the safety and efficacy of treatments. However, trial timelines are severely delayed with minimal success due to a multitude of factors, including imperfect trial site selection, cohort recruitment challeng...
Trial Factors Associated With Completion of Clinical Trials Evaluating AI: Retrospective Case-Control Study.
Journal of medical Internet research
Sep 23, 2024
BACKGROUND: Evaluation of artificial intelligence (AI) tools in clinical trials remains the gold standard for translation into clinical settings. However, design factors associated with successful trial completion and the common reasons for trial fai...
Artificial Intelligence and cancer: Profile of registered clinical trials.
Journal of cancer policy
Sep 4, 2024
Artificial Intelligence (AI) has made significant strides due to advancements in processing algorithms and data availability. Recent years have shown a resurgence in AI, driven by breakthroughs in deep machine learning. AI has attracted particular in...
Enhancing Patient Selection in Sepsis Clinical Trials Design Through an AI Enrichment Strategy: Algorithm Development and Validation.
Journal of medical Internet research
Sep 4, 2024
BACKGROUND: Sepsis is a heterogeneous syndrome, and enrollment of more homogeneous patients is essential to improve the efficiency of clinical trials. Artificial intelligence (AI) has facilitated the identification of homogeneous subgroups, but how t...
Ethical Considerations in the Design and Conduct of Clinical Trials of Artificial Intelligence.
JAMA network open
Sep 3, 2024
IMPORTANCE: Safe integration of artificial intelligence (AI) into clinical settings often requires randomized clinical trials (RCT) to compare AI efficacy with conventional care. Diabetic retinopathy (DR) screening is at the forefront of clinical AI ...
Generative AI intervention clinical trials: a call for pre-registration - correspondence.
International journal of surgery (London, England)
Sep 1, 2024
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