International journal of radiation oncology, biology, physics
Mar 29, 2025
PURPOSE: Recent advances in artificial intelligence (AI) have showcased the potential of automatic treatment planning for clinical trials involving radiation therapy. This paper offers an overview of the current landscape of AI-based treatment planni...
BACKGROUND AND OBJECTIVES: Among the participants of Alzheimer disease (AD) treatment trials, 40% do not show cognitive decline over 80 weeks of follow-up. Identifying and excluding these individuals can increase power to detect treatment effects. We...
BACKGROUND: Despite the rapid growth of research in artificial intelligence/machine learning (AI/ML), little is known about how often study results are disclosed years after study completion.
PURPOSE OF REVIEW: The uses of generative artificial intelligence (GAI) technologies in medicine are expanding, with the use of large language models (LLMs) for matching patients to clinical trials of particular interest. This review provides an over...
BACKGROUND: Identifying patients eligible for clinical trials through eligibility screening is time and resource-intensive. Natural Language Processing (NLP) models may enhance clinical trial screening by extracting data from Electronic Health Record...
Clinical trials are pivotal in drug development yet fraught with uncertainties and resource-intensive demands. The application of AI models to forecast trial outcomes could mitigate failures and expedite the drug discovery process. This review discus...
Therapeutic innovation & regulatory science
Feb 25, 2025
The traditional clinical trial monitoring process, which relies heavily on site visits and manual review of accumulative patient data reported through Electronic Data Capture system, is time-consuming and resource-intensive. The recently emerged risk...
Innovations such as artificial intelligence (AI) and decentralized clinical trials (DCTs) offer opportunities to enhance trial quality and efficiency. However, these innovations raise ethical questions about key responsibilities in research, such as ...
This article examines the transformative potential of blockchain technology and its integration with artificial intelligence (AI) in clinical trials, focusing on their combined ability to enhance integrity, operational efficiency, and transparency in...
International journal of radiation oncology, biology, physics
Jan 22, 2025
This white paper examines the potential of pioneering technologies and artificial intelligence-driven solutions in advancing clinical trials involving radiation therapy. As the field of radiation therapy evolves, the integration of cutting-edge appro...
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