AIMC Topic: Clonidine

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Prediction of Side Effects Using Comprehensive Similarity Measures.

BioMed research international Feb 27, 2020
Identifying the potential side effects of drugs is crucial in clinical trials in the pharmaceutical industry. The existing side effect prediction methods mainly focus on the chemical and biological properties of drugs. This study proposes a method th...
Drug Interactions Drug-Related Side Effects and Adverse Reactions Humans Drug Repositioning Area Under Curve Machine Learning Clonidine Polymorphism, Single Nucleotide Dasatinib Sitagliptin Phosphate Vorinostat
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Facilitatory effects of anti-spastic medication on robotic locomotor training in people with chronic incomplete spinal cord injury.

Journal of neuroengineering and rehabilitation Mar 20, 2015
BACKGROUND: The objective of this study was to investigate whether an anti-spasticity medication can facilitate the effects of robotic locomotor treadmill training (LTT) to improve gait function in people with incomplete spinal cord injury (SCI).
Robotics Walking Muscle, Skeletal Muscle Strength Locomotion Spinal Cord Injuries Gait Range of Motion, Articular Biomechanical Phenomena Male Middle Aged Treatment Outcome Aged Adult Female Muscle Spasticity Humans Clonidine Isometric Contraction Muscle Relaxants, Central Learning
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Spontaneous withdrawal in intermittent morphine administration in rats and mice: effect of clonidine coadministration and sex-related differences.

Turkish journal of medical sciences Jan 1, 2015
BACKGROUND/AIM: Treating animals repeatedly with intermittent and increasing morphine doses has been suggested to allow some withdrawal during each dosing interval, which causes repeated stress. The present study aimed to test this hypothesis and ass...
Substance Withdrawal Syndrome Narcotic Antagonists Sex Factors Drug Administration Schedule Analgesics, Opioid Morphine Mice, Inbred Strains Rats, Wistar Clonidine Dose-Response Relationship, Drug Naloxone Grooming Animals Mice, Inbred BALB C Female Analgesics Male
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Comparison between the therapeutic effects of robotic-assisted locomotor training and an anti-spastic medication on spasticity.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Jan 1, 2015
We studied the effects of robotic-assisted locomotor (LOKOMAT) training or an anti-spastic medication (tizanidine) on neuromuscular abnormality associated with spasticity in persons with incomplete Spinal Cord Injury (SCI). Subjects were randomly div...
Robotics Electromyography Range of Motion, Articular Humans Spinal Cord Injuries Muscle Relaxants, Central Physical Therapy Modalities Muscle Spasticity Clonidine Ankle Joint Motor Activity
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