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Mice, Inbred Strains

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Spontaneous withdrawal in intermittent morphine administration in rats and mice: effect of clonidine coadministration and sex-related differences.

Turkish journal of medical sciences
BACKGROUND/AIM: Treating animals repeatedly with intermittent and increasing morphine doses has been suggested to allow some withdrawal during each dosing interval, which causes repeated stress. The present study aimed to test this hypothesis and ass...

Single subject transcriptome analysis to identify functionally signed gene set or pathway activity.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Analysis of single-subject transcriptome response data is an unmet need of precision medicine, made challenging by the high dimension, dynamic nature and difficulty in extracting meaningful signals from biological or stochastic noise. We have propose...

Machine vision analysis on abnormal respiratory conditions of mice inhaling particles containing cadmium.

Ecotoxicology and environmental safety
Inhalable environmental toxicants can induce pulmonary malfunction resulting abnormal respiratory conditions. The traditional methods currently available to detect the respiratory condition of animals rely on differential pressure transducers and sig...