Rare diseases affect 1-in-10 people in the United States and despite increased genetic testing, up to half never receive a diagnosis. Even when using advanced genome sequencing platforms to discover variants, if there is no connection between the var...
Journal of cardiovascular electrophysiology
Dec 23, 2024
INTRODUCTION: Catheter ablation of persistent atrial fibrillation yields sub-optimal success rates partly due to the considerable heterogeneity within the patient population. Identifying distinct patient phenotypes based on post-ablation prognosis co...
BACKGROUND: Globally, pre-eclampsia (PE) poses a major threat to the health and survival of pregnant women and fetuses, contributing significantly to morbidity and mortality. Recent studies suggest a pathological link between PE and ferroptosis. We a...
Neural networks : the official journal of the International Neural Network Society
Dec 20, 2024
Multi-view clustering can better handle high-dimensional data by combining information from multiple views, which is important in big data mining. However, the existing models which simply perform feature fusion after feature extraction for individua...
Emotion recognition through artificial intelligence and smart sensing of physical and physiological signals (affective computing) is achieving very interesting results in terms of accuracy, inference times, and user-independent models. In this sense,...
BACKGROUND: Electronic medical records (EMR)-trained machine learning models have the potential in CVD risk prediction by integrating a range of medical data from patients, facilitate timely diagnosis and classification of CVDs. We tested the hypothe...
Perimeter Intrusion Detection Systems (PIDS) are crucial for protecting any physical locations by detecting and responding to intrusions around its perimeter. Despite the availability of several PIDS, challenges remain in detection accuracy and preci...
Interdisciplinary sciences, computational life sciences
Dec 16, 2024
The advent of spatially resolved transcriptomics (SRT) has provided critical insights into the spatial context of tissue microenvironments. Spatial clustering is a fundamental aspect of analyzing spatial transcriptomics data. However, spatial cluster...
European journal of internal medicine
Dec 16, 2024
BACKGROUND: Obstructive sleep apnea (OSA) is a heterogeneous sleep disorder for which the identification of phenotypes might help for risk stratification for long-term mortality. Thus, the aim of the study was to identify distinct phenotypes of OSA a...
Journal of computational biology : a journal of computational molecular cell biology
Dec 13, 2024
With the continuous evolution of single-cell RNA sequencing technology, it has become feasible to reconstruct cell development processes using computational methods. Trajectory inference is a crucial downstream analytical task that provides valuable ...
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