Deep neural networks have been successfully applied to generate predictive patterns from medical and diagnostic data. This paper presents an approach for assessing persons with Alzheimer's disease (AD) mild cognitive impairment (MCI), compared with n...
Progress in neuro-psychopharmacology & biological psychiatry
Nov 14, 2022
OBJECTIVE: To develop and validate artificial intelligence models for the prediction of cognitive impairment in chronic kidney disease (CKD) patients using structural and functional brain network.
Physical and engineering sciences in medicine
Nov 10, 2022
The study aims to implement a convolutional neural network framework that uses the 18F-FDG PET modality of brain imaging to detect multiple stages of dementia, including Early Mild Cognitive Impairment (EMCI) and Late Mild Cognitive Impairment (LMCI)...
An objective biomarker to predict the outcome of isolated rapid eye movement sleep behavior disorder (iRBD) is crucial for the management. This study aimed to investigate cognitive signature of brain [F]FDG PET based on deep learning (DL) for evaluat...
International journal of psychophysiology : official journal of the International Organization of Psychophysiology
Oct 27, 2022
Alzheimer's disease (AD), a neurodegenerative disorder characterized by progressive cognitive decline, is generally prevalent in elderly people with significant disability and mortality. There is no effective treatment for AD currently, but the early...
Early diagnosis of Alzheimer's disease plays a pivotal role in patient care and clinical trials. In this study, we have developed a new approach based on 3D deep convolutional neural networks to accurately differentiate mild Alzheimer's disease demen...
Age-related cognitive impairment is multifactorial, with numerous underlying and frequently co-morbid pathological correlates. Amyloid beta (Aβ) plays a major role in Alzheimer's type age-related cognitive impairment, in addition to other etiopatholo...
Patients with Mild Cognitive Impairment (MCI) have an increased risk of Alzheimer's disease (AD). Early identification of underlying neurodegenerative processes is essential to provide treatment before the disease is well established in the brain. He...
In Alzheimer's disease, the molecular pathogenesis of the extracellular Aβ-amyloid (Aβ) instigation of intracellular tau accumulation is poorly understood. We employed a high-resolution PET scanner, with low detection thresholds, to examine the Aβ-ta...