Stem cell-derived organoids are a promising tool to model native human tissues as they resemble human organs functionally and structurally compared to traditional monolayer cell-based assays. For instance, colon organoids can spontaneously develop cr...
United European gastroenterology journal
Oct 12, 2022
Endoscopic remission is now considered the ultimate long-term goal for treating inflammatory bowel disease (IBD). Recent advances in endoscopic techniques have progressively added new tools to the armamentarium of endoscopists for a deeper assessment...
Tortuosity of the colon is an important parameter for predicting the course of colonoscopy. Computed tomography scans of the abdominal cavity were performed in 224 (94 female, 130 male) adult subjects. The number of acute (angle not exceeding 90°) be...
Inflammatory bowel disease (IBD) is a chronic immune-mediated disease of the gastrointestinal tract. While therapies exist, response can be limited within the patient population. Researchers have thus studied mouse models of colitis to further unders...
BACKGROUND: Colon cancer resection can be technically difficult in the obese (OB) population. Robotic surgery is a promising technique but its benefits remain uncertain in OB patients. The aim of this study is to compare OB versus non-obese (NOB) pat...
Pixel-wise error correction of initial segmentation results provides an effective way for quality improvement. The additional error segmentation network learns to identify correct predictions and incorrect ones. The performance on error segmentation ...
Evodiamine (Evo) is an alkaloid that can be extracted from the berry fruit and has been reported to exert various pharmacological effects, such as antidiarrheal, antiemetic and antiulcer effects. , the potential effects of Evo were investigated in a...
Most patients with Crohn disease (CD), a chronic inflammatory gastrointestinal disease, experience recurrence despite treatment, including surgical resection. However, methods for predicting recurrence remain unclear. This study aimed to predict post...
Medical & biological engineering & computing
Jan 19, 2022
Developments in deep learning have resulted in computer-aided diagnosis for many types of cancer. Previously, pathologists manually performed the labeling work in the analysis of colon tissues, which is both time-consuming and labor-intensive. Result...
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