Colorectal cancer (CRC) is the second popular cancer in females and third in males, with an increased number of cases. Pathology diagnoses complemented with predictive and prognostic biomarker information is the first step for personalized treatment....
Colorectal cancer plays a dominant role in cancer-related deaths, primarily due to the absence of obvious early-stage symptoms. Whole-stage colorectal disease diagnosis is crucial for assessing lesion evolution and determining treatment plans. Howeve...
BACKGROUND:  Artificial intelligence (AI) systems in endoscopy are predominantly developed and tested using high-quality imagery from expert centers. However, their performance may be different when applied in clinical practice, partly due to the div...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Jan 30, 2025
Mismatch repair deficiency (dMMR), also known as high-grade microsatellite instability (MSI-H), is a well-established biomarker for predicting the immunotherapy response in endometrial cancer (EC) and colorectal cancer (CRC). Tumor mutational burden ...
BACKGROUND: The rising number of cancer survivors and the shortage of health care professionals challenge the accessibility of cancer care. Health technologies are necessary for sustaining optimal patient journeys. To understand individuals' daily li...
OBJECTIVES: Adenomatous colorectal polyps require endoscopic resection, as opposed to non-adenomatous hyperplastic colorectal polyps. This study aims to evaluate the effect of artificial intelligence (AI)-assisted differentiation of adenomatous and n...
Biochimica et biophysica acta. Molecular basis of disease
Jan 25, 2025
Drug resistance often stems from drug-tolerant persister (DTP) cells in cancer. These cells arise from various lineages and exhibit complex dynamics. However, effectively targeting DTP cells remains challenging. We used single-cell RNA sequencing (sc...
The current work introduces the hybrid ensemble framework for the detection and segmentation of colorectal cancer. This framework will incorporate both supervised classification and unsupervised clustering methods to present more understandable and a...
BACKGROUND: Perineural invasion (PNI) in colorectal cancer (CRC) is a significant prognostic factor associated with poor outcomes. Radiomics, which involves extracting quantitative features from medical imaging, has emerged as a potential tool for pr...
Medical & biological engineering & computing
Jan 21, 2025
In computer-aided diagnosis systems, precise feature extraction from CT scans of colorectal cancer using deep learning is essential for effective prognosis. However, existing convolutional neural networks struggle to capture long-range dependencies a...
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