Although advancing the therapeutic alternatives for treating deadly cancers has gained much attention globally, still the primary methods such as chemotherapy have significant downsides and low specificity. Most recently, Anticancer peptides (ACPs) h...
Stochastic models of biomolecular reaction networks are commonly employed in systems and synthetic biology to study the effects of stochastic fluctuations emanating from reactions involving species with low copy-numbers. For such models, the Kolmogor...
Computational and mathematical methods in medicine
Dec 8, 2021
One of the most common visual disorders is cataracts, which people suffer from as they get older. The creation of a cloud on the lens of our eyes is known as a cataract. Blurred vision, faded colors, and difficulty seeing in strong light are the main...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
The advancements of single-cell RNA sequencing (scRNA-seq) technologies have provided us unprecedented opportunities to characterize cellular states and investigate the mechanisms of complex diseases. Due to technical issues such as dropout events, s...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
A novel coronavirus (COVID-19) recently emerged as an acute respiratory syndrome, and has caused a pneumonia outbreak world-widely. As the COVID-19 continues to spread rapidly across the world, computed tomography (CT) has become essentially importan...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
The identification of cancer subtypes is of great importance for understanding the heterogeneity of tumors and providing patients with more accurate diagnoses and treatments. However, it is still a challenge to effectively integrate multiple omics da...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Non-coding RNA (ncRNA) is involved in many biological processes and diseases in all species. Many ncRNA datasets exist that provide ncRNA data in FASTA format which is well suited for biomedical purposes. However, for ncRNA analysis and classificatio...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Myocardial infarctions and heart failure are the cause of more than 17 million deaths annually worldwide. ST-segment elevation myocardial infarctions (STEMI) require timely treatment, because delays of minutes have serious clinical impacts. Machine l...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
The identification of a protein fold type from its amino acid sequence provides important insights about the protein 3D structure. In this paper, we propose a deep learning architecture that can process protein residue-level features to address the p...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Clustering tumor metastasis samples from gene expression data at the whole genome level remains an arduous challenge, in particular, when the number of experimental samples is small and the number of genes is huge. We focus on the prediction of the e...
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