AIMC Topic: Computer Simulation

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Exploring temporal information in neonatal seizures using a dynamic time warping based SVM kernel.

Computers in biology and medicine Jan 26, 2017
Seizure events in newborns change in frequency, morphology, and propagation. This contextual information is explored at the classifier level in the proposed patient-independent neonatal seizure detection system. The system is based on the combination...
Sensitivity and Specificity Humans Male Models, Statistical Spatio-Temporal Analysis Algorithms Diagnosis, Computer-Assisted Female Pattern Recognition, Automated Epilepsy, Benign Neonatal Computer Simulation Electrocardiography Infant, Newborn Support Vector Machine Reproducibility of Results
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Master-Leader-Slave Cuckoo Search with Parameter Control for ANN Optimization and Its Real-World Application to Water Quality Prediction.

PloS one Jan 26, 2017
Artificial neural networks (ANNs) have been employed to solve a broad variety of tasks. The selection of an ANN model with appropriate weights is important in achieving accurate results. This paper presents an optimization strategy for ANN model sele...
Water Quality Algorithms Computer Simulation Models, Theoretical Neural Networks, Computer
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Classification of sphingosine kinase inhibitors using counter propagation artificial neural networks: A systematic route for designing selective SphK inhibitors.

SAR and QSAR in environmental research Jan 25, 2017
Accurate and robust classification models for describing and predicting the activity of 330 chemicals that are sphingosine kinase 1 (SphK1) and/or sphingosine kinase 2 (SphK2) inhibitors were derived. The classification models developed in this work ...
Neural Networks, Computer Phosphotransferases (Alcohol Group Acceptor) ROC Curve Algorithms Enzyme Inhibitors Computer Simulation Chemistry, Pharmaceutical Drug Discovery
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Arbitrary Symmetric Running Gait Generation for an Underactuated Biped Model.

PloS one Jan 24, 2017
This paper investigates generating symmetric trajectories for an underactuated biped during the stance phase of running. We use a point mass biped (PMB) model for gait analysis that consists of a prismatic force actuator on a massless leg. The signif...
Energy Metabolism Leg Humans Gait Computer Simulation Models, Biological Robotics Running Equipment Design Biomechanical Phenomena Posture
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Rapid Design of Knowledge-Based Scoring Potentials for Enrichment of Near-Native Geometries in Protein-Protein Docking.

PloS one Jan 24, 2017
Protein-protein docking protocols aim to predict the structures of protein-protein complexes based on the structure of individual partners. Docking protocols usually include several steps of sampling, clustering, refinement and re-scoring. The scorin...
Monte Carlo Method Protein Interaction Mapping Knowledge Bases Linear Models Protein Conformation Algorithms Computer Simulation Molecular Docking Simulation Protein Binding Software Models, Molecular Models, Chemical
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Support Vector Machine Classification of Drunk Driving Behaviour.

International journal of environmental research and public health Jan 23, 2017
Alcohol is the root cause of numerous traffic accidents due to its pharmacological action on the human central nervous system. This study conducted a detection process to distinguish drunk driving from normal driving under simulated driving condition...
Male Eye Movements Support Vector Machine Driving Under the Influence Principal Component Analysis Automobile Driving Humans Computer Simulation
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Neuromorphic meets neuromechanics, part II: the role of fusimotor drive.

Journal of neural engineering Jan 17, 2017
OBJECTIVE: We studied the fundamentals of muscle afferentation by building a Neuro-mechano-morphic system actuating a cadaveric finger. This system is a faithful implementation of the stretch reflex circuitry. It allowed the systematic exploration of...
Humans Computer Simulation Animals Models, Neurological Synaptic Transmission Afferent Pathways Action Potentials Signal Processing, Computer-Assisted Muscle Spindles Muscle, Skeletal Biomimetics Robotics Motor Neurons, Gamma Muscle Contraction Neuromuscular Junction
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Link prediction in drug-target interactions network using similarity indices.

BMC bioinformatics Jan 17, 2017
BACKGROUND: In silico drug-target interaction (DTI) prediction plays an integral role in drug repositioning: the discovery of new uses for existing drugs. One popular method of drug repositioning is network-based DTI prediction, which uses complex ne...
Databases, Factual Computer Simulation Support Vector Machine Drug Repositioning
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Three-Class Mammogram Classification Based on Descriptive CNN Features.

BioMed research international Jan 15, 2017
In this paper, a novel classification technique for large data set of mammograms using a deep learning method is proposed. The proposed model targets a three-class classification study (normal, malignant, and benign cases). In our model we have prese...
Mammography Databases as Topic Wavelet Analysis Humans Reproducibility of Results Neural Networks, Computer Image Processing, Computer-Assisted Computer Simulation Support Vector Machine
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Neuromorphic meets neuromechanics, part I: the methodology and implementation.

Journal of neural engineering Jan 13, 2017
OBJECTIVE: One goal of neuromorphic engineering is to create 'realistic' robotic systems that interact with the physical world by adopting neuromechanical principles from biology. Critical to this is the methodology to implement the spinal circuitry ...
Muscle, Skeletal Robotics Signal Processing, Computer-Assisted Animals Models, Neurological Action Potentials Motor Neurons Afferent Pathways Muscle Spindles Humans Biomimetics Neuromuscular Junction Computer Simulation Muscle Contraction Synaptic Transmission
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