AIMC Topic: COVID-19
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Optimizing microfluidic chip for rapid SARS-CoV-2 detection using Taguchi method and artificial neural network PSO.
Scientific reports
Apr 23, 2025
Microfluidic biosensors offer a promising solution for real-time analysis of coronaviruses with minimal sample volumes. This study optimizes a biochip for the rapid detection of SARS-CoV-2 using the Taguchi orthogonal table L(3), which comprises nine...
Design of nanobody targeting SARS-CoV-2 spike glycoprotein using CDR-grafting assisted by molecular simulation and machine learning.
PLoS computational biology
Apr 21, 2025
The design of proteins capable effectively binding to specific protein targets is crucial for developing therapies, diagnostics, and vaccine candidates for viral infections. Here, we introduce a complementarity-determining region (CDR) grafting appro...
CAD-Unet: A capsule network-enhanced Unet architecture for accurate segmentation of COVID-19 lung infections from CT images.
Medical image analysis
Apr 19, 2025
Since the outbreak of the COVID-19 pandemic in 2019, medical imaging has emerged as a primary modality for diagnosing COVID-19 pneumonia. In clinical settings, the segmentation of lung infections from computed tomography images enables rapid and accu...
Large-Scale Deep Learning-Enabled Infodemiological Analysis of Substance Use Patterns on Social Media: Insights From the COVID-19 Pandemic.
JMIR infodemiology
Apr 17, 2025
BACKGROUND: The COVID-19 pandemic intensified the challenges associated with mental health and substance use (SU), with societal and economic upheavals leading to heightened stress and increased reliance on drugs as a coping mechanism. Centers for Di...
Combining machine learning and dynamic system techniques to early detection of respiratory outbreaks in routinely collected primary healthcare records.
BMC medical research methodology
Apr 16, 2025
BACKGROUND: Methods that enable early outbreak detection represent powerful tools in epidemiological surveillance, allowing adequate planning and timely response to disease surges. Syndromic surveillance data collected from primary healthcare encount...
Advancing Pedagogy in Leadership Practice to Enhance Public Health Impact.
Journal of public health management and practice : JPHMP
Apr 15, 2025
BACKGROUND: The COVID-19 pandemic highlighted the critical need for competent leadership in public health to address emergent health challenges and restore trust in health institutions. Emphasizing leadership training in public health education progr...
Changes in recreational drug use, reasons for those changes and their consequence during and after the COVID-19 pandemic in the UK.
Comprehensive psychiatry
Apr 15, 2025
Changes in drug use in the general population during the COVID-19 pandemic and their long-term consequences are not well understood. We employed natural language processing and machine learning to analyse a large dataset of self-reported rates of and...
Machine Learning Interpretation of Optical Spectroscopy Using Peak-Sensitive Logistic Regression.
ACS nano
Apr 15, 2025
Optical spectroscopy, a noninvasive molecular sensing technique, offers valuable insights into material characterization, molecule identification, and biosample analysis. Despite the informativeness of high-dimensional optical spectra, their interpre...
Unraveling relevant cross-waves pattern drifts in patient-hospital risk factors among hospitalized COVID-19 patients using explainable machine learning methods.
BMC infectious diseases
Apr 15, 2025
BACKGROUND: Several studies explored factors related to adverse clinical outcomes among COVID-19 patients but lacked analysis of the impact of the temporal data shifts on the strength of association between different predictors and adverse outcomes. ...
Remdesivir associated with reduced mortality in hospitalized COVID-19 patients: treatment effectiveness using real-world data and natural language processing.
BMC infectious diseases
Apr 12, 2025
BACKGROUND: Remdesivir (RDV) was the first antiviral approved for mild-to-moderate COVID-19 and for those patients at risk for progression to severe disease after clinical trials supported its association with improved outcomes. Real-world evidence (...
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