The international journal of biostatistics
May 1, 2016
Consider one observes n i.i.d. copies of a random variable with a probability distribution that is known to be an element of a particular statistical model. In order to define our statistical target we partition the sample in V equal size sub-samples...
The international journal of biostatistics
May 1, 2016
Comparing the relative fit of competing models can be used to address many different scientific questions. In classical statistics one can, if appropriate, use likelihood ratio tests and information based criterion, whereas clinical medicine has tend...
The international journal of biostatistics
May 1, 2016
This paper investigates the appropriateness of the integration of flexible propensity score modeling (nonparametric or machine learning approaches) in semiparametric models for the estimation of a causal quantity, such as the mean outcome under treat...
Combinatorial chemistry & high throughput screening
Jan 1, 2016
BACKGROUND: Docking allows to predict ligand binding to proteins, since the 3D-structure for the target is available. Several docking studies have been carried out to identify potential ligands for drug targets. Many of these studies resulted in the ...
Advances in anatomy, embryology, and cell biology
Jan 1, 2016
Bioimage informatics is a field wherein high-throughput image informatics methods are used to solve challenging scientific problems related to biology and medicine. When the image datasets become larger and more complicated, many conventional image a...
Machine learning addresses the question of how to build computers that improve automatically through experience. It is one of today's most rapidly growing technical fields, lying at the intersection of computer science and statistics, and at the core...
Financial markets emanate massive amounts of data from which machines can, in principle, learn to invest with minimal initial guidance from humans. I contrast human and machine strengths and weaknesses in making investment decisions. The analysis rev...
Research report (Health Effects Institute)
Jun 1, 2015
INTRODUCTION: The United States Environmental Protection Agency (U.S. EPA*) currently regulates individual air pollutants on a pollutant-by-pollutant basis, adjusted for other pollutants and potential confounders. However, the National Academies of S...
IEEE transactions on neural networks and learning systems
Feb 1, 2015
Reservoir computing is a paradigm in machine learning whose processing capabilities rely on the dynamical behavior of recurrent neural networks. We present a mixed analog and digital implementation of this concept with a nonlinear analog electronic c...
Technology and health care : official journal of the European Society for Engineering and Medicine
Jan 1, 2015
BACKGROUND: To collect medical datasets, it is usually the case that a number of data samples contain some missing values. Performing the data mining task over the incomplete datasets is a difficult problem. In general, missing value imputation can b...
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