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Why Cohen's Kappa should be avoided as performance measure in classification.

PloS one
We show that Cohen's Kappa and Matthews Correlation Coefficient (MCC), both extended and contrasted measures of performance in multi-class classification, are correlated in most situations, albeit can differ in others. Indeed, although in the symmetr...

Automated diagnosis of heart valve degradation using novelty detection algorithms and machine learning.

PloS one
The blood flow through the major vessels holds great diagnostic potential for the identification of cardiovascular complications and is therefore routinely assessed with current diagnostic modalities. Heart valves are subject to high hydrodynamic loa...

Practical High-Quality Electrostatic Potential Surfaces for Drug Discovery Using a Graph-Convolutional Deep Neural Network.

Journal of medicinal chemistry
Inspecting protein and ligand electrostatic potential (ESP) surfaces in order to optimize electrostatic complementarity is a key activity in drug design. These ESP surfaces need to reflect the true electrostatic nature of the molecules, which typical...

Deep Learning and Glaucoma Specialists: The Relative Importance of Optic Disc Features to Predict Glaucoma Referral in Fundus Photographs.

Ophthalmology
PURPOSE: To develop and validate a deep learning (DL) algorithm that predicts referable glaucomatous optic neuropathy (GON) and optic nerve head (ONH) features from color fundus images, to determine the relative importance of these features in referr...

Artificially intelligent scoring and classification engine for forensic identification.

Forensic science international. Genetics
Despite advances in genotyping technologies, traditional kinship analysis tools utilized in forensic identification have seen limited evolution and lack measures of accuracy. Here, we leverage artificial intelligence (AI) and extend the Elston-Stewar...

Human Gait Recognition Based on Frame-by-Frame Gait Energy Images and Convolutional Long Short-Term Memory.

International journal of neural systems
Human gait recognition is one of the most promising biometric technologies, especially for unobtrusive video surveillance and human identification from a distance. Aiming at improving recognition rate, in this paper we study gait recognition using de...

Hover-Net: Simultaneous segmentation and classification of nuclei in multi-tissue histology images.

Medical image analysis
Nuclear segmentation and classification within Haematoxylin & Eosin stained histology images is a fundamental prerequisite in the digital pathology work-flow. The development of automated methods for nuclear segmentation and classification enables th...

Combined tract segmentation and orientation mapping for bundle-specific tractography.

Medical image analysis
While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to reproduce...

econvRBP: Improved ensemble convolutional neural networks for RNA binding protein prediction directly from sequence.

Methods (San Diego, Calif.)
RNA binding proteins (RBPs) determine RNA process from synthesis to decay, which play a key role in RNA transport, translation and degradation. Therefore, exploring RBPs' function from the amino acid sequence using computational methods has become on...