AIMC Topic: Deep Learning

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MISPEL: A supervised deep learning harmonization method for multi-scanner neuroimaging data.

Medical image analysis
Large-scale data obtained from aggregation of already collected multi-site neuroimaging datasets has brought benefits such as higher statistical power, reliability, and robustness to the studies. Despite these promises from growth in sample size, sub...

DLATA: Deep Learning-Assisted transformation alignment of 2D brain slice histology.

Neuroscience letters
Accurate alignment of brain slices is crucial for the classification of neuron populations by brain region, and for quantitative analysis in in vitro brain studies. Current semi-automated alignment workflows require labor intensive labeling of featur...

Deep learning reconstruction for brain diffusion-weighted imaging: efficacy for image quality improvement, apparent diffusion coefficient assessment, and intravoxel incoherent motion evaluation in and studies.

Diagnostic and interventional radiology (Ankara, Turkey)
PURPOSE: Deep learning reconstruction (DLR) to improve imaging quality has already been introduced, but no studies have evaluated the effect of DLR on diffusion-weighted imaging (DWI) or intravoxel incoherent motion (IVIM) in or studies. The purpos...

Development of a deep learning model for safe direct optical trocar insertion in minimally invasive surgery: an innovative method to prevent trocar injuries.

Surgical endoscopy
BACKGROUND: Direct optical trocar insertion is a common procedure in laparoscopic minimally invasive surgery. However, misinterpretations of the abdominal wall anatomy can lead to severe complications. Artificial intelligence has shown promise in sur...

GENERA: A Combined Genetic/Deep-Learning Algorithm for Multiobjective Target-Oriented De Novo Design.

Journal of chemical information and modeling
This study introduces a new de novo design algorithm called that combines the capabilities of a deep-learning algorithm for automated drug-like analogue design, called , with a genetic algorithm for generating molecules with desired target-oriented ...

De Novo Design of κ-Opioid Receptor Antagonists Using a Generative Deep-Learning Framework.

Journal of chemical information and modeling
Likely effective pharmacological interventions for the treatment of opioid addiction include attempts to attenuate brain reward deficits during periods of abstinence. Pharmacological blockade of the κ-opioid receptor (KOR) has been shown to abolish b...

Image Quality Improvement in Deep Learning Image Reconstruction of Head Computed Tomography Examination.

Tomography (Ann Arbor, Mich.)
In this study, we assess image quality in computed tomography scans reconstructed via DLIR (Deep Learning Image Reconstruction) and compare it with iterative reconstruction ASIR-V (Adaptive Statistical Iterative Reconstruction) in CT (computed tomogr...

DeepAIR: A deep learning framework for effective integration of sequence and 3D structure to enable adaptive immune receptor analysis.

Science advances
Structural docking between the adaptive immune receptors (AIRs), including T cell receptors (TCRs) and B cell receptors (BCRs), and their cognate antigens are one of the most fundamental processes in adaptive immunity. However, current methods for pr...

Transferring From Textual Entailment to Biomedical Named Entity Recognition.

IEEE/ACM transactions on computational biology and bioinformatics
Biomedical Named Entity Recognition (BioNER) aims at identifying biomedical entities such as genes, proteins, diseases, and chemical compounds in the given textual data. However, due to the issues of ethics, privacy, and high specialization of biomed...

A deep learning model for accurately predicting cancer-specific survival in patients with primary bone sarcoma of the extremity: a population-based study.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
PURPOSE: Primary bone and joint sarcomas of the long bone are relatively rare neoplasms with poor prognosis. An efficient clinical tool that can accurately predict patient prognosis is not available. The current study aimed to use deep learning algor...