AIMC Topic: Deep Learning

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Exploring Implicit Biological Heterogeneity in ASD Diagnosis Using a Multi-Head Attention Graph Neural Network.

Journal of integrative neuroscience
BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental disorder exhibiting heterogeneous characteristics in patients, including variability in developmental progression and distinct neuroanatomical features influenced by sex and age. Rece...

[Constructing a cataplexy face prediction model for narcolepsy type 1 based on ResNet-18].

Zhonghua yi xue za zhi
To establish a prediction model for the identifying of cataplexy facial features based on clinical shooting videos by using a deep learning image recognition network ResNet-18. A cross-sectional study. Twenty-five narcolepsy type 1 patients who wer...

A deep learning approach to direct immunofluorescence pattern recognition in autoimmune bullous diseases.

The British journal of dermatology
BACKGROUND: Artificial intelligence (AI) is reshaping healthcare, using machine and deep learning (DL) to enhance disease management. Dermatology has seen improved diagnostics, particularly in skin cancer detection, through the integration of AI. How...

Predicting Obstructive Sleep Apnea Based on Computed Tomography Scans Using Deep Learning Models.

American journal of respiratory and critical care medicine
The incidence of clinically undiagnosed obstructive sleep apnea (OSA) is high among the general population because of limited access to polysomnography. Computed tomography (CT) of craniofacial regions obtained for other purposes can be beneficial i...

DDMut-PPI: predicting effects of mutations on protein-protein interactions using graph-based deep learning.

Nucleic acids research
Protein-protein interactions (PPIs) play a vital role in cellular functions and are essential for therapeutic development and understanding diseases. However, current predictive tools often struggle to balance efficiency and precision in predicting t...

Deep learning for the PSIPRED Protein Analysis Workbench.

Nucleic acids research
The PSIRED Workbench is a long established and popular bioinformatics web service offering a wide range of machine learning based analyses for characterizing protein structure and function. In this paper we provide an update of the recent additions a...

AIUPred: combining energy estimation with deep learning for the enhanced prediction of protein disorder.

Nucleic acids research
Intrinsically disordered proteins and protein regions (IDPs/IDRs) carry out important biological functions without relying on a single well-defined conformation. As these proteins are a challenge to study experimentally, computational methods play im...

Deep-PK: deep learning for small molecule pharmacokinetic and toxicity prediction.

Nucleic acids research
Evaluating pharmacokinetic properties of small molecules is considered a key feature in most drug development and high-throughput screening processes. Generally, pharmacokinetics, which represent the fate of drugs in the human body, are described fro...

Automating Wood Species Detection and Classification in Microscopic Images of Fibrous Materials with Deep Learning.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
We have developed a methodology for the systematic generation of a large image dataset of macerated wood references, which we used to generate image data for nine hardwood genera. This is the basis for a substantial approach to automate, for the firs...

TransCell: In Silico Characterization of Genomic Landscape and Cellular Responses by Deep Transfer Learning.

Genomics, proteomics & bioinformatics
Gene expression profiling of new or modified cell lines becomes routine today; however, obtaining comprehensive molecular characterization and cellular responses for a variety of cell lines, including those derived from underrepresented groups, is no...