Enhancer-promoter interactions (EPIs) play an important role in transcriptional regulation. Recently, machine learning-based methods have been widely used in the genome-scale identification of EPIs due to their promising predictive performance. In th...
Human papillomavirus (HPV) integrating into human genome is the main cause of cervical carcinogenesis. HPV integration selection preference shows strong dependence on local genomic environment. Due to this theory, it is possible to predict HPV integr...
MOTIVATION: The functional changes of the genes, RNAs and proteins will eventually be reflected in the metabolic level. Increasing number of researchers have researched mechanism, biomarkers and targeted drugs by metabolites. However, compared with o...
Long noncoding RNAs (lncRNAs) play significant roles in various physiological and pathological processes via their interactions with biomolecules like DNA, RNA and protein. The existing in silico methods used for predicting the functions of lncRNA ma...
Mathematical biosciences and engineering : MBE
Jul 16, 2021
The purpose of this study was to explore whether the Nomogram, which was constructed by combining the Deep learning and Radiomic features of T2-weighted MR images with Clinical factors (NDRC), could accurately predict placenta invasion. This retrospe...
BACKGROUND: Technology to restore the ability to communicate in paralyzed persons who cannot speak has the potential to improve autonomy and quality of life. An approach that decodes words and sentences directly from the cerebral cortical activity of...
There is a growing interest among quantitative geneticists and animal breeders in the use of deep learning (DL) for genomic prediction. However, the performance of DL is affected by hyperparameters that are typically manually set by users. These hype...
Journal of the American Medical Informatics Association : JAMIA
Jul 14, 2021
OBJECTIVE: Accessing medical data from multiple institutions is difficult owing to the interinstitutional diversity of vocabularies. Standardization schemes, such as the common data model, have been proposed as solutions to this problem, but such sch...
Journal of the American Medical Informatics Association : JAMIA
Jul 14, 2021
OBJECTIVE: Due to the COVID-19 pandemic, our daily habits have suddenly changed. Gatherings are forbidden and, even when it is possible to leave the home for health or work reasons, it is necessary to wear a face mask to reduce the possibility of con...
Journal of the American Medical Informatics Association : JAMIA
Jul 14, 2021
OBJECTIVE: Automated analysis of vaccine postmarketing surveillance narrative reports is important to understand the progression of rare but severe vaccine adverse events (AEs). This study implemented and evaluated state-of-the-art deep learning algo...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.