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Dementia

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Prediction of Alzheimer's disease dementia with MRI beyond the short-term: Implications for the design of predictive models.

NeuroImage. Clinical
Magnetic resonance imaging (MRI) volumetric measures have become a standard tool for the detection of incipient Alzheimer's Disease (AD) dementia in mild cognitive impairment (MCI). Focused on providing an earlier and more accurate diagnosis, sophist...

Machine learning approaches to studying the role of cognitive reserve in conversion from mild cognitive impairment to dementia.

International journal of geriatric psychiatry
OBJECTIVES: The overall aim of the present study was to explore the role of cognitive reserve (CR) in the conversion from mild cognitive impairment (MCI) to dementia. We used traditional and machine learning (ML) techniques to compare converter and n...

Arterial Spin Labeling Images Synthesis From sMRI Using Unbalanced Deep Discriminant Learning.

IEEE transactions on medical imaging
Adequate medical images are often indispensable in contemporary deep learning-based medical imaging studies, although the acquisition of certain image modalities may be limited due to several issues including high costs and patients issues. However, ...

Harnessing the Power of Machine Learning in Dementia Informatics Research: Issues, Opportunities, and Challenges.

IEEE reviews in biomedical engineering
Dementia is a chronic and degenerative condition affecting millions globally. The care of patients with dementia presents an ever-continuing challenge to healthcare systems in the 21st century. Medical and health sciences have generated unprecedented...

Detection of abnormal behaviour for dementia sufferers using Convolutional Neural Networks.

Artificial intelligence in medicine
In recent years, there is a rapid increase in the population of elderly people. However, elderly people may suffer from the consequences of cognitive decline, which is a mental health disorder that primarily affects cognitive abilities such as learni...

Machine learning methods for detecting urinary tract infection and analysing daily living activities in people with dementia.

PloS one
Dementia is a neurological and cognitive condition that affects millions of people around the world. At any given time in the United Kingdom, 1 in 4 hospital beds are occupied by a person with dementia, while about 22% of these hospital admissions ar...

Antemortem CSF A42/A40 ratio predicts Alzheimer's disease pathology better than A42 in rapidly progressive dementias.

Annals of clinical and translational neurology
OBJECTIVE: Despite the critical importance of pathologically confirmed samples for biomarker validation, only a few studies have correlated CSF A42 values in vivo with postmortem Alzheimer's disease (AD) pathology, while none evaluated the CSF A42/A4...

Pet robot intervention for people with dementia: A systematic review and meta-analysis of randomized controlled trials.

Psychiatry research
This study aims to systematically evaluate the efficacy of Pet robot intervention (PRI) for people with dementia. Two waves of electronic searches of the PubMed, EMBASE, Web of Science, Cochrane library, IEEE Digital Library and PsycINFO databases we...

Disease Trajectories and End-of-Life Care for Dementias: Latent Topic Modeling and Trend Analysis Using Clinical Notes.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Despite the increasing prevalence, growing costs, and high mortality of dementia in older adults in the U.S., little is known about the course of these diseases and what care dementia patients receive in their final years of life. Using a large volum...