AIMC Topic: Depressive Disorder, Major
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The efficacy of topological properties of functional brain networks in identifying major depressive disorder.
Scientific reports
Nov 27, 2024
Major Depressive Disorder (MDD) is a common mental disorder characterized by cognitive impairment, and its pathophysiology remains to be explored. In this study, we aimed to explore the efficacy of brain network topological properties (TPs) in identi...
Disentangling the Genetic Landscape of Peripartum Depression: A Multi-Polygenic Machine Learning Approach on an Italian Sample.
Genes
Nov 26, 2024
BACKGROUND: The genetic determinants of peripartum depression (PPD) are not fully understood. Using a multi-polygenic score approach, we characterized the relationship between genome-wide information and the history of PPD in patients with mood disor...
Altered Blood Oxygen Level-Dependent Signal Stability in the Brain of Patients with Major Depressive Disorder Undergoing Resting-State Functional Magnetic Resonance Imaging.
Neuropsychobiology
Nov 26, 2024
INTRODUCTION: Major depressive disorder (MDD) is a common, relapse-prone psychiatric disorder with unknown pathogenesis. Previous studies on resting-state functional magnetic resonance imaging of MDD have mostly focused on the spontaneous activity of...
Development and Validation of a Prediction Model for Co-Occurring Moderate-to-Severe Anxiety Symptoms in First-Episode and Drug Naïve Patients With Major Depressive Disorder.
Depression and anxiety
Nov 19, 2024
Moderate-to-severe anxiety symptoms are severe and common in patients with major depressive disorder (MDD) and have a significant impact on MDD patients and their families. The main objective of this study was to develop a risk prediction model for ...
An adaptive multi-graph neural network with multimodal feature fusion learning for MDD detection.
Scientific reports
Nov 18, 2024
Major Depressive Disorder (MDD) is an affective disorder that can lead to persistent sadness and a decline in the quality of life, increasing the risk of suicide. Utilizing multimodal data such as electroencephalograms and patient interview audios ca...
The voice of depression: speech features as biomarkers for major depressive disorder.
BMC psychiatry
Nov 12, 2024
BACKGROUND: Psychiatry faces a challenge due to the lack of objective biomarkers, as current assessments are based on subjective evaluations. Automated speech analysis shows promise in detecting symptom severity in depressed patients. This project ai...
Optimizing the Prediction of Depression Remission: A Longitudinal Machine Learning Approach.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
Oct 29, 2024
Decisions about when to change antidepressant treatment are complex and benefit from accurate prediction of treatment outcome. Prognostic accuracy can be enhanced by incorporating repeated assessments of symptom severity collected during treatment. P...
Development of machine-learning-driven signatures for diagnosing and monitoring therapeutic response in major depressive disorder using integrated immune cell profiles and plasma cytokines.
Theranostics
Oct 28, 2024
Diagnosis and treatment efficacy of major depressive disorder (MDD) currently lack stable and reliable biomarkers. Previous research has suggested a potential association between immune cells, cytokines, and the pathophysiology and treatment of MDD....
Resting-State Electroencephalogram Depression Diagnosis Based on Traditional Machine Learning and Deep Learning: A Comparative Analysis.
Sensors (Basel, Switzerland)
Oct 23, 2024
The global prevalence of Major Depressive Disorder (MDD) is increasing at an alarming rate, underscoring the urgent need for timely and accurate diagnoses to facilitate effective interventions and treatments. Electroencephalography remains a widely u...
Peripheral Blood Mononuclear Cell Biomarkers for Major Depressive Disorder: A Transcriptomic Approach.
Depression and anxiety
Oct 3, 2024
Major depressive disorder (MDD) is a complex condition characterized by persistent depressed mood, loss of interest or pleasure, loss of energy or fatigue, and, in severe case, recurrent thoughts of death. Despite its prevalence, reliable diagnostic...
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