AIMC Topic: Drugs, Chinese Herbal

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Neural network analysis of Chinese herbal medicine prescriptions for patients with colorectal cancer.

Complementary therapies in medicine
Traditional Chinese Medicine (TCM) is an experiential form of medicine with a history dating back thousands of years. The present study aimed to utilize neural network analysis to examine specific prescriptions for colorectal cancer (CRC) in clinical...

Application of Chemometric Algorithms in the High-Performance Thin-Layer Chromatography Fingerprint of Traditional Chinese Medicines.

Journal of AOAC International
The use of HPTLC fingerprinting for the analysis of traditional Chinese medicines (TCMs) usually involves several image-processing steps. However, these image-processing steps are time consuming. We describe a new approach that applies artificial n...

Discovery of quality control markers from traditional Chinese medicines by fingerprint-efficacy modeling: Current status and future perspectives.

Journal of pharmaceutical and biomedical analysis
Quality control (QC) is crucial for ensuring the safety and effectiveness of traditional Chinese medicines (TCMs). Due to extremely complicated phytochemical matrices and characteristic mode of "multi-component, multi-target, integrated adjustment", ...

Optimization of ionic liquids-based microwave-assisted hydrolysis of puerarin and daidzein derivatives from Radix Puerariae Lobatae extract.

Food chemistry
Ionic liquids-based microwave-assisted hydrolysis was successfully applied for hydrolysis of puerarin and daidzein derivatives from Radix Puerariae Lobatae extract. The ionic liquids with different cations and anions have been investigated, and [Omim...

Putative identification of components in Zengye Decoction and their effects on glucose consumption and lipogenesis in insulin-induced insulin-resistant HepG2 cells.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Zengye Decoction (ZYD) is a well-known traditional medicine in China used for treating diseases associated with "Yin deficiency" such as diabetes. However, little information is available on its components, pharmacological effects and underlying mech...

Nanoparticle based bio-bar code technology for trace analysis of aflatoxin B1 in Chinese herbs.

Journal of food and drug analysis
A novel and sensitive assay for aflatoxin B1 (AFB1) detection has been developed by using bio-bar code assay (BCA). The method that relies on polyclonal antibodies encoded with DNA modified gold nanoparticle (NP) and monoclonal antibodies modified ma...

A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae.

Molecules (Basel, Switzerland)
(Wuweizi in Chinese), a common traditional Chinese herbal medicine, has been used for centuries to treat chronic liver disease. The therapeutic efficacy of Wuweizi has also been validated in clinical practice. In this study, molecular docking and ne...

Detection of lithospermate B in rat plasma at the nanogram level by LC/MS in multi reaction monitoring mode.

Journal of food and drug analysis
Low bioavailability and high binding affinity to plasma proteins led to the difficulty for the quantitative detection of lithospermate B (LSB) in plasma. This study aimed to develop a protocol for detecting LSB in plasma. A method was employed to qua...

DisArticle: a web server for SVM-based discrimination of articles on traditional medicine.

BMC complementary and alternative medicine
BACKGROUND: Much research has been done in Northeast Asia to show the efficacy of traditional medicine. While MEDLINE contains many biomedical articles including those on traditional medicine, it does not categorize those articles by specific researc...

[Effect of the Chinese Herbal Medicinal Ingredients in Huoxiang Zhengqi Liquid on Alcohol Metabolism in Rats].

Fa yi xue za zhi
OBJECTIVES: To study the changes of alcohol content and pharmacokinetic parameter in rats after taking Huoxiang Zhengqi liquid.