AIMC Topic: Epilepsies, Partial
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STIED: a deep learning model for the spatiotemporal detection of focal interictal epileptiform discharges with MEG.
Scientific reports
Jul 1, 2025
Magnetoencephalography (MEG) allows the non-invasive detection of interictal epileptiform discharges (IEDs). Clinical MEG analysis in epileptic patients traditionally relies on the visual identification of IEDs, which is time consuming and partially ...
Decision support system based on ensemble models in distinguishing epilepsy types.
Epilepsy & behavior : E&B
May 17, 2025
This study aimed to classify patients' focal (frontal, temporal, parietal, occipital), multifocal, and generalized epileptiform activities based on EEG findings using artificial intelligence models. The study included 575 patients followed in the Neu...
Understanding the Spatio-Temporal Coupling of Spikes and Spindles in Focal Epilepsy Through a Network-Level Computational Model.
International journal of neural systems
Mar 15, 2025
The electrophysiological findings have shown that epileptiform spikes triggering sleep spindles within 1[Formula: see text]s across multiple channels are commonly observed during sleep in focal epilepsy (FE). Such spatio-temporal couplings of spikes ...
Pseudo-HFOs Elimination in iEEG Recordings Using a Robust Residual-Based Dictionary Learning Framework.
IEEE journal of biomedical and health informatics
Feb 10, 2025
High-frequency oscillations (HFOs) in intracranial EEG (iEEG) recordings are critical biomarkers for localizing the seizure onset zone (SOZ) in patients with focal refractory epilepsy. Despite their clinical significance, HFO analysis is often compro...
Neuropathology of focal epilepsy: the promise of artificial intelligence and digital Neuropathology 3.0.
Pathology
Dec 19, 2024
Focal lesions of the human neocortex often cause drug-resistant epilepsy, yet surgical resection of the epileptogenic region has been proven as a successful strategy to control seizures in a carefully selected patient cohort. Continuous efforts to s...
Seizure Sources Can Be Imaged from Scalp EEG by Means of Biophysically Constrained Deep Neural Networks.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Oct 29, 2024
Seizure localization is important for managing drug-resistant focal epilepsy. Here, the capability of a novel deep learning-based source imaging framework (DeepSIF) for imaging seizure activities from electroencephalogram (EEG) recordings in drug-res...
Practical measurements distinguishing physiological and pathological stereoelectroencephalography channels based on high-frequency oscillations in the human brain.
Epilepsia open
May 29, 2024
OBJECTIVE: The present study aimed to identify various distinguishing features for use in the accurate classification of stereoelectroencephalography (SEEG) channels based on high-frequency oscillations (HFOs) inside and outside the epileptogenic zon...
Construction and validation of an algorithm to separate focal and generalised epilepsy using clinical variables: A comparison of machine learning approaches.
Epilepsy & behavior : E&B
Apr 25, 2024
PURPOSE: Epilepsy type, whether focal or generalised, is important in deciding anti-seizure medication (ASM). In resource-limited settings, investigations are usually not available, so a clinical separation is required. We used a naïve Bayes approach...
Attention-based deep convolutional neural network for classification of generalized and focal epileptic seizures.
Epilepsy & behavior : E&B
Apr 17, 2024
Epilepsy affects over 50 million people globally. Electroencephalography is critical for epilepsy diagnosis, but manual seizure classification is time-consuming and requires extensive expertise. This paper presents an automated multi-class seizure cl...
Protocol of a prospective multicenter randomized controlled trial of robot-assisted stereotactic lesioning in the treatment of focal drug-resistant epilepsy.
Trials
Jun 9, 2023
BACKGROUND: This protocol describes the design of a multicenter randomized controlled trial of robot-assisted stereotactic lesioning versus epileptogenic foci resection. Typical causes of focal epilepsy include hippocampal sclerosis and focal cortica...
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