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Evidence-Based Medicine

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Precision population analytics: population management at the point-of-care.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: To present clinicians at the point-of-care with real-world data on the effectiveness of various treatment options in a precision cohort of patients closely matched to the index patient.

Artificial intelligence and automation of systematic reviews in women's health.

Current opinion in obstetrics & gynecology
PURPOSE OF REVIEW: Evidence-based women's healthcare is underpinned by systematic reviews and guidelines. Generating an evidence synthesis to support guidance for clinical practice is a time-consuming and labour-intensive activity that delays transfe...

A NICE perspective on computable biomedical knowledge.

BMJ health & care informatics
INTRODUCTION: The National Institute for Health and Care Excellence (NICE) plays a central role in the NHS. We distill knowledge of best practice from the best available sources of evidence and share this across the health and care system, typically ...

Quadruple Decision Making for Parkinson's Disease Patients: Combining Expert Opinion, Patient Preferences, Scientific Evidence, and Big Data Approaches to Reach Precision Medicine.

Journal of Parkinson's disease
Clinical decision making for Parkinson's disease patients is supported by a combination of three distinct information resources: best available scientific evidence, professional expertise, and the personal needs and preferences of patients. All three...

Pretraining to Recognize PICO Elements from Randomized Controlled Trial Literature.

Studies in health technology and informatics
PICO (Population/problem, Intervention, Comparison, and Outcome) is widely adopted for formulating clinical questions to retrieve evidence from the literature. It plays a crucial role in Evidence-Based Medicine (EBM). This paper contributes a scalabl...

An outcome model approach to transporting a randomized controlled trial results to a target population.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Participants enrolled into randomized controlled trials (RCTs) often do not reflect real-world populations. Previous research in how best to transport RCT results to target populations has focused on weighting RCT data to look like the tar...