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Serological proteomic characterization for monitoring liver fibrosis regression in chronic hepatitis B patients on treatment.

Nature communications
Longitudinal serological proteomic dynamics during antiviral therapy (AVT) in chronic hepatitis B (CHB) patients with liver fibrosis remain poorly characterized. Here, using four-dimensional data-independent acquisition mass spectrometry (4D-DIA-MS),...

Machine learning-based construction of Immunogenic cell death-related score for improving prognosis and personalized treatment in glioma.

Scientific reports
Immunogenic cell death (ICD) is capable of activating both innate and adaptive immune responses. In this study, we aimed to develop an ICD-related signature in glioma patients and facilitate the assessment of their prognosis and drug sensitivity. Con...

Extended length of stay in open versus minimally invasive surgery with robotic-assisted sub-analysis for spinal nerve sheath tumor resection: a nationwide analysis.

Scientific reports
Spinal nerve sheath tumors are slow-growing neoplasms that arise from Schwann cell lineage and encompass schwannomas, neurofibromas, hybrid nerve sheath tumors, and malignant peripheral nerve sheath tumors. These lesions most commonly present as intr...

Human expert grading versus automated quantification of fluid volumes in nAMD, DME and BRVO.

Scientific reports
This study compared an automated deep learning algorithm with certified human graders from the Vienna Reading Center (VRC) in identifying intra- (IRF) and subretinal fluid (SRF) in OCT scans of patients treated for neovascular age-related macular deg...

Plasma interleukin-22 concentration and disease activity in inflammatory bowel disease.

Scientific reports
The relationship between interleukin-22 and clinical characteristics of patients with inflammatory bowel disease is uncertain. We sought to determine whether plasma interleukin-22 concentrations are associated with disease activity in a large populat...

Comparative performance of deep learning architectures for diabetic peripheral neuropathy detection using corneal confocal microscopy: a retrospective single-centre study.

BMJ open
OBJECTIVES: This study aims to develop a deep learning algorithm (DLA) using the InceptionV3 architecture for effective diabetic peripheral neuropathy (DPN) screening via corneal confocal microscopy (CCM) images.

Acceptance of AI-Powered Chatbots Among Physiotherapy Students: International Cross-Sectional Study.

JMIR medical education
BACKGROUND: Artificial intelligence-powered chatbots (AI-PCs) are increasingly integrated into educational settings, including health care disciplines. Despite their potential to enhance learning, limited research has investigated physiotherapy (PT) ...

Data-driven cognitive subtypes in major depressive disorder: Grey matter atrophy in the left fusiform gyrus and cerebellum.

Journal of affective disorders
BACKGROUND: This study aims to apply a semi-supervised machine learning approach for classifying major depressive disorder (MDD) patients into more homogeneous cognitive subtypes based on multidimensional cognitive profiles, and to perform multimodal...

Establishing Clinically Distinct Patient Treatment Subgroups Following Anterior Cruciate Ligament Reconstruction: A Machine Learning Clustering Analysis.

The American journal of sports medicine
BACKGROUND: Treatment decisions in patients with anterior cruciate ligament (ACL) injuries are influenced by multiple factors, such as the desire to return to sports or symptomatic instability. Identifying the differential treatment effect of ACL rec...

Determination of Skeletal Age From Hand Radiographs Using Deep Learning.

The American journal of sports medicine
BACKGROUND: Surgeons treating skeletally immature patients use skeletal age to determine appropriate surgical strategies. Traditional bone age estimation methods utilizing hand radiographs are time-consuming.