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Psoas muscle CT radiomics-based machine learning models to predict response to infliximab in patients with Crohn's disease.
Annals of medicine
Jul 5, 2025
BACKGROUND: Crohn's disease (CD) is a chronic inflammatory bowel disease, with infliximab (IFX) commonly used for treatment. However, no clinically applicable model currently exists to predict the response of patients with CD to IFX therapy. Given th...
Neuroimaging and biological markers of different paretic hand outcomes after stroke.
Journal of neuroengineering and rehabilitation
Jul 5, 2025
BACKGROUND: Hand dysfunction significantly affects independence after stroke, with outcomes varying across individuals. Exploring biomarkers associated with the paretic hand can improve the prognosis and guide personalized rehabilitation. However, wh...
Assessing chronic obstructive pulmonary disease risk based on exhalation and cough sounds.
Biomedical engineering online
Jul 5, 2025
BACKGROUND AND OBJECTIVE: Chronic obstructive pulmonary disease (COPD), a progressively worsening respiratory condition, severely impacts patient quality of life. Early risk assessment can improve treatment outcomes and lessen healthcare burdens. How...
Serum tryptophan-kynurenine metabolites served as biomarkers of disease activity in rheumatoid arthritis and linked to immune imbalance.
Arthritis research & therapy
Jul 5, 2025
BACKGROUND: Immune imbalance caused by imbalanced helper T(Th)17/regulatory T (Treg) and follicular helper T (Tfh)/follicular regulatory T (Tfr) cells drives the onset of rheumatoid arthritis (RA) fundamentally. Tryptophan (Trp) metabolism is crucial...
Employing machine learning for early detection of poly-victimization in rural children: a survey study in China's Chaoshan region.
BMC public health
Jul 5, 2025
BACKGROUND: Poly-victimization (PV), encompassing multiple forms of victimization including physical abuse, emotional maltreatment, neglect, and peer violence, poses a significant public health challenge among children, particularly in rural areas wi...
Wristful thinking: exploring the effects of robotic rehabilitation and cross-education for persons with multiple sclerosis.
Journal of neuroengineering and rehabilitation
Jul 5, 2025
The goal of this work was to develop an adaptive rehabilitation technique using a haptic wrist robot that would induce cross-education to an untrained limb. Fourteen individuals with Multiple Sclerosis (MS) and eight non-affected adults completed an ...
Generative artificial intelligence in entrepreneurship education enhances entrepreneurial intention through self-efficacy and university support.
Scientific reports
Jul 5, 2025
This study investigates how Generative Artificial Intelligence Supported Entrepreneurship Education (GAISEE) influences university students' entrepreneurial intentions through a quantitative analysis of Chinese higher education institutions. Using st...
Impact of generative AI interaction and output quality on university students' learning outcomes: a technology-mediated and motivation-driven approach.
Scientific reports
Jul 5, 2025
This study investigates the influence of generative artificial intelligence (GAI) on university students' learning outcomes, employing a technology-mediated learning perspective. We developed and empirically tested an integrated model, grounded in in...
Predictive modeling and machine learning show poor performance of clinical, morphological, and hemodynamic parameters for small intracranial aneurysm rupture.
Scientific reports
Jul 5, 2025
Small intracranial aneurysms (SIAs) (< 5 mm) are increasingly detected due to advanced imaging, but predicting rupture risk remains challenging. Rupture, though rare, can cause devastating subarachnoid hemorrhage. This study analyzed 141 SIAs (101 un...
Multi-kingdom microbiota analysis reveals bacteria-viral interplay in IBS with depression and anxiety.
NPJ biofilms and microbiomes
Jul 5, 2025
Irritable Bowel Syndrome (IBS) is a common gastrointestinal disorder frequently accompanied by psychological symptoms. Bacterial microbiota plays a critical role in mediating local and systemic immunity, and alterations in these microbial communities...
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