AIMC Topic: Genetic Therapy

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Recent Progress of Machine Learning in Gene Therapy.

Current gene therapy
With new developments in biomedical technology, it is now a viable therapeutic treatment to alter genes with techniques like CRISPR. At the same time, it is increasingly cheaper to perform whole genome sequencing, resulting in rapid advancement in ge...

The retina revolution: signaling pathway therapies, genetic therapies, mitochondrial therapies, artificial intelligence.

Current opinion in ophthalmology
PURPOSE OF REVIEW: The aim of this article is to review and discuss the history, current state, and future implications of promising biomedical offerings in the field of retina.

Recent developments in pediatric retina.

Current opinion in ophthalmology
PURPOSE OF REVIEW: Pediatric retina is an exciting, but also challenging field, where patient age and cooperation can limit ease of diagnosis of a broad range of congenital and acquired diseases, inherited retinal degenerations are mostly untreatable...

Future Vision 2020 and Beyond-5 Critical Trends in Eye Research.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
Ophthalmology has been at the forefront of many innovations in basic science and clinical research. The randomized prospective multicenter clinical trial, comparative clinical trials, the bench to beside development of diagnostic and therapeutic devi...

Deep Forest-based Prediction of Protein Subcellular Localization.

Current gene therapy
MOTIVATION: Knowledge of the correct protein subcellular localization is necessary for understanding the function of a protein and revealing the mechanism of many human diseases due to protein subcellular mislocalization, which is required before app...

A Brief Survey of Machine Learning Application in Cancerlectin Identification.

Current gene therapy
Proteins with at least one carbohydrate recognition domain are lectins that can identify and reversibly interact with glycan moiety of glycoconjugates or a soluble carbohydrate. It has been proved that lectins can play various vital roles in mediatin...

[Research of enhanced green fluorescent protein gene transfer with ultrasound-mediated microbubble destruction in bone defects].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
OBJECTIVE: To investigate the effect of ultrasonic irradiation time on enhanced green fluorescent protein (EGFP) gene transfection efficiency and local tissue in bone defects using ultrasound-mediated microbubble destruction.

Smart Micro/Nano-robotic Systems for Gene Delivery.

Current gene therapy
BACKGROUND: Small scale robotics have attracted growing attention for the prospect of targeting and accessing cell-sized sites, necessary for high precision biomedical applications and drug/gene delivery. The loss of controlled gene therapy, inducing...