AIMC Topic: Glaucoma, Open-Angle

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Use of Machine Learning on Contact Lens Sensor-Derived Parameters for the Diagnosis of Primary Open-angle Glaucoma.

American journal of ophthalmology
PURPOSE: To test the hypothesis that contact lens sensor (CLS)-based 24-hour profiles of ocular volume changes contain information complementary to intraocular pressure (IOP) to discriminate between primary open-angle glaucoma (POAG) and healthy (H) ...

Detection of Longitudinal Visual Field Progression in Glaucoma Using Machine Learning.

American journal of ophthalmology
PURPOSE: Global indices of standard automated perimerty are insensitive to localized losses, while point-wise indices are sensitive but highly variable. Region-wise indices sit in between. This study introduces a machine learning-based index for glau...

Predictions of ocular changes caused by diabetes in glaucoma patients.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: This paper builds different neural network models with simple topologies, having one or two hidden layers which were subsequently employed in the prediction of ocular changes progression in patients with diabetes associated ...

Screening of Glaucoma in High-Risk Minority Populations.

Journal of glaucoma
PRECIS: This chapter reviews the current recommendations on screening for open angle glaucoma in Black and Hispanic populations. Strategies for increasing case-finding and decreasing cost, with emphasis on evolving technologies, are presented.

Accelerated Biological Aging in Exfoliation Glaucoma Assessed by Fundus-Derived Predicted Age and Advanced Glycation End Products.

International journal of molecular sciences
Glaucoma is an age-related neurodegenerative disease characterized by progressive optic nerve damage. Accelerated biological aging, assessed using predicted age derived from fundus images, may serve as a biomarker for glaucoma progression. This study...

Identification and validation of oxidative stress-related genes in primary open-angle glaucoma by weighted gene co-expression network analysis and machine learning.

Medicine
Primary open-angle glaucoma (POAG) is a common ocular disease, and there is currently no effective treatment for POAG therapy. Thus, identifying some effective diagnostic markers is beneficial to the treatment of patients. The expression profile was ...

Deep Learning Identifies High-Quality Fundus Photographs and Increases Accuracy in Automated Primary Open Angle Glaucoma Detection.

Translational vision science & technology
PURPOSE: To develop and evaluate a deep learning (DL) model to assess fundus photograph quality, and quantitatively measure its impact on automated POAG detection in independent study populations.

Detecting Glaucoma in the Ocular Hypertension Study Using Deep Learning.

JAMA ophthalmology
IMPORTANCE: Automated deep learning (DL) analyses of fundus photographs potentially can reduce the cost and improve the efficiency of reading center assessment of end points in clinical trials.

Identifying the Retinal Layers Linked to Human Contrast Sensitivity Via Deep Learning.

Investigative ophthalmology & visual science
PURPOSE: Luminance contrast is the fundamental building block of human spatial vision. Therefore contrast sensitivity, the reciprocal of contrast threshold required for target detection, has been a barometer of human visual function. Although retinal...