AIMC Topic: Glaucoma, Open-Angle

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A Deep Learning Algorithm to Quantify Neuroretinal Rim Loss From Optic Disc Photographs.

American journal of ophthalmology
PURPOSE: To train a deep learning (DL) algorithm that quantifies glaucomatous neuroretinal damage on fundus photographs using the minimum rim width relative to Bruch membrane opening (BMO-MRW) from spectral-domain optical coherence tomography (SDOCT)...

Use of Machine Learning on Contact Lens Sensor-Derived Parameters for the Diagnosis of Primary Open-angle Glaucoma.

American journal of ophthalmology
PURPOSE: To test the hypothesis that contact lens sensor (CLS)-based 24-hour profiles of ocular volume changes contain information complementary to intraocular pressure (IOP) to discriminate between primary open-angle glaucoma (POAG) and healthy (H) ...

Detection of Longitudinal Visual Field Progression in Glaucoma Using Machine Learning.

American journal of ophthalmology
PURPOSE: Global indices of standard automated perimerty are insensitive to localized losses, while point-wise indices are sensitive but highly variable. Region-wise indices sit in between. This study introduces a machine learning-based index for glau...

Predictions of ocular changes caused by diabetes in glaucoma patients.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: This paper builds different neural network models with simple topologies, having one or two hidden layers which were subsequently employed in the prediction of ocular changes progression in patients with diabetes associated ...

Prediction of perimetric progression in ocular hypertension and open angle glaucoma based on corneal biomechanics.

European journal of ophthalmology
PurposeTo identify parameters that are significant risk predictors of visual field (VF) progression in patients with ocular hypertension (OHT) or early primary open-angle glaucoma (POAG), using Goldmann applanation tonometry intraocular pressure (IOP...

Accelerated Biological Aging in Exfoliation Glaucoma Assessed by Fundus-Derived Predicted Age and Advanced Glycation End Products.

International journal of molecular sciences
Glaucoma is an age-related neurodegenerative disease characterized by progressive optic nerve damage. Accelerated biological aging, assessed using predicted age derived from fundus images, may serve as a biomarker for glaucoma progression. This study...

Identification and validation of oxidative stress-related genes in primary open-angle glaucoma by weighted gene co-expression network analysis and machine learning.

Medicine
Primary open-angle glaucoma (POAG) is a common ocular disease, and there is currently no effective treatment for POAG therapy. Thus, identifying some effective diagnostic markers is beneficial to the treatment of patients. The expression profile was ...