AIMC Topic: Gold

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Ligand supplementation restores the cancer therapy efficacy of the antirheumatic drug auranofin from serum inactivation.

Nature communications Aug 9, 2025
Auranofin, an FDA-approved antirheumatic gold drug, has gained ongoing interest in clinical studies for treating advanced or recurrent tumors. However, gold ion's dynamic thiol exchange nature strongly attenuates its bioactivity due to the fast forma...
Antirheumatic Agents Auranofin Cell Line, Tumor Mice Gold Sulfhydryl Compounds Ligands Xenograft Model Antitumor Assays Animals Humans Neoplasms Female Antineoplastic Agents
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Lateral flow and colorimetric assay for ketamine detection reinforced with deep learning model interfaced with mobile app for smart alert.

Mikrochimica acta Aug 9, 2025
Point-of-care (POC) devices have grown in popularity due to their ease of use, low cost, and speedy on-site diagnostic capabilities. This study focuses on ketamine detection by colorimetric and lateral flow assays (LFA), with aptamer-based LFA emergi...
Point-of-Care Systems Deep Learning Colorimetry Humans Metal Nanoparticles Limit of Detection Ketamine Aptamers, Nucleotide Mobile Applications Gold
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Urea-mediated growth engineering of Au@Ag core-shell nanostructures: an enzymatic detection strategy with machine learning-assisted comparative analysis.

Mikrochimica acta Jul 29, 2025
A non-invasive, enzyme-based colorimetric biosensor was developed for urea detection in saliva, utilizing a growth-based method with Au@Ag core-shell nanostructures, including CTAB-coated gold nanoparticles (AuNPs) and CTAB-coated gold nanorods with ...
Biosensing Techniques Gold Metal Nanoparticles Humans Machine Learning Colorimetry Saliva Urea Nanotubes Limit of Detection Silver Urease
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Fabrication of serum-based SERS-tailored 3D structures for thyroid cancer diagnosis.

Scientific reports Jul 1, 2025
Early detection of thyroid cancer improves patient survival rate from 51.9% to 99.9%. Fine needle aspiration cytology is the primary method for diagnosing thyroid cancer; however, this method is associated with limitations, including diagnostic uncer...
Metal Nanoparticles Biomarkers, Tumor Neural Networks, Computer Machine Learning Male Humans Spectrum Analysis, Raman Female Thyroid Neoplasms Printing, Three-Dimensional Gold
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Deforestation driven by illegal and informal gold mining in the southern Peruvian Amazon: a predictive land use analysis over the next 50 years.

Environmental monitoring and assessment Jun 23, 2025
The Amazon is recognized not only for its vast biodiversity and territorial extent but also for the significant mineral riches it harbors. This potential has intensified small-scale illegal and informal gold mining, a practice often employed without ...
Environmental Monitoring Gold Forests Peru Conservation of Natural Resources Mining
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Split DNA Tetrahedron-Mediated Spatiotemporal-Hierarchy CRISPR Cascade Integrated with Au@Pt Nanolabels and Artificial Intelligence for a Cervical Cancer MicroRNA Bioassay.

ACS nano Jun 11, 2025
The screening and monitoring of microRNAs as cancer molecular biomarkers is clinically significant, but traditional methods lack sufficient sensitivity, accuracy, and convenience. The CRISPR-colorimetric lateral flow assay (CLFA) integration offers a...
MicroRNAs DNA Gold Metal Nanoparticles CRISPR-Cas Systems Platinum Artificial Intelligence Female Uterine Cervical Neoplasms Humans
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Exploring the role of density functional theory in the design of gold nanoparticles for targeted drug delivery: a systematic review.

Journal of molecular modeling Jun 10, 2025
CONTEXT: Targeted drug delivery systems leveraging gold nanoparticles (AuNPs) demand precise atomic-level design to overcome current limitations in drug-loading efficiency and controlled release. Unlike previous focused reviews, this systematic analy...
Gold Metal Nanoparticles Drug Delivery Systems Drug Design Density Functional Theory Humans
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Deep learning based rapid X-ray fluorescence signal extraction and image reconstruction for preclinical benchtop X-ray fluorescence computed tomography applications.

Scientific reports Jun 4, 2025
Recent research advances have resulted in an experimental benchtop X-ray fluorescence computed tomography (XFCT) system that likely meets the imaging dose/scan time constraints for benchtop XFCT imaging of live mice injected with gold nanoparticles (...
Neural Networks, Computer Phantoms, Imaging Tomography, X-Ray Computed Mice Animals Gold Deep Learning Metal Nanoparticles Image Processing, Computer-Assisted
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TCN-QV: an attention-based deep learning method for long sequence time-series forecasting of gold prices.

PloS one May 5, 2025
Accurate prediction of gold prices is crucial for investment decision-making and national risk management. The time series data of gold prices exhibits random fluctuations, non-linear characteristics, and high volatility, making prediction extremely ...
Gold Forecasting Humans Commerce Deep Learning Neural Networks, Computer China
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Synergistic detection of E. coli using ultrathin film of functionalized graphene with impedance spectroscopy and machine learning.

Scientific reports Apr 30, 2025
Bacterial detection and classification are critical challenges in healthcare, environmental monitoring, and food safety, demanding selective and efficient methods. This study presents a novel, label-free approach for E. coli detection using ultrathin...
Dielectric Spectroscopy Humans Electrodes Machine Learning Graphite Escherichia coli Gold
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