AIMC Topic: Urease

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Unveiling the role of microbial rease in ureolysis-induced calcium carbonate precipitation, Its mechanistic insights, and emerging applications.

World journal of microbiology & biotechnology Jun 25, 2025
Urease (urea amidohydrolase, EC 3.5.1.5) is a metalloenzyme that catalyzes the hydrolysis of urea into ammonia and carbamate, playing a pivotal role in numerous biotechnological applications. Initially sourced from plants (such as Canavalia ensiformi...
Bacteria Urease Biotechnology Calcium Carbonate Sporosarcina Fungi Chemical Precipitation Urea
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Machine Learning-Driven Classification of Urease Inhibitors Leveraging Physicochemical Properties as Effective Filter Criteria.

International journal of molecular sciences Apr 13, 2024
Urease, a pivotal enzyme in nitrogen metabolism, plays a crucial role in various microorganisms, including the pathogenic . Inhibiting urease activity offers a promising approach to combating infections and associated ailments, such as chronic kidney...
Urease Helicobacter pylori Enzyme Inhibitors Humans Machine Learning Algorithms
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Anti-inflammatory and urease inhibitory iridoid glycosides from Nyctanthes arbor-tristis Linn.

Journal of ethnopharmacology Oct 30, 2023
ETHNOPHARMACOLOGICAL RELEVANCE: Nyctanthes arbor-tristis Linn. has been used by Ayruvedic physicians for the cure of different diseases including ulcers, gastric and inflammatory diseases.
Anti-Inflammatory Agents Mice Urease Tumor Necrosis Factor-alpha Kinetics Plant Extracts Iridoid Glycosides Animals Reactive Oxygen Species Molecular Docking Simulation
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Enzyme-Photocatalyst Tandem Microrobot Powered by Urea for Escherichia coli Biofilm Eradication.

Small (Weinheim an der Bergstrasse, Germany) Feb 5, 2022
Urinary-based infections affect millions of people worldwide. Such bacterial infections are mainly caused by Escherichia coli (E. coli) biofilm formation in the bladder and/or urinary catheters. Herein, the authors present a hybrid enzyme/photocataly...
Escherichia coli Robotics Catalysis Humans Biofilms Titanium Urease Urea
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Amino acid conjugated antimicrobial drugs: Synthesis, lipophilicity- activity relationship, antibacterial and urease inhibition activity.

European journal of medicinal chemistry Dec 29, 2017
Present work describes the in vitro antibacterial evaluation of some new amino acid conjugated antimicrobial drugs. Structural modification was attempted on the three existing antimicrobial pharmaceuticals namely trimethoprim, metronidazole, isoniazi...
Bacillus Structure-Activity Relationship Isoniazid Anti-Bacterial Agents Trimethoprim Molecular Structure Microbial Sensitivity Tests Amino Acids Salmonella typhi Hydrophobic and Hydrophilic Interactions Escherichia coli Enzyme Inhibitors Staphylococcus aureus Urease Dose-Response Relationship, Drug Metronidazole Pseudomonas aeruginosa
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Predictive Analysis of Dental Caries Risk via Rapid Urease Activity Evaluation in Saliva Using a ZIF-8 Nanoporous Membrane.

ACS sensors Jun 27, 2025
Despite a decrease in the incidence of dental caries over the past four decades, it remains a widespread public health concern. The multifactorial etiology of dental caries complicates effective prevention and early intervention efforts, underscoring...
Nanopores Saliva Zeolites Humans Membranes, Artificial Dental Caries Urease
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Swarming behavior and in vivo monitoring of enzymatic nanomotors within the bladder.

Science robotics Mar 17, 2021
Enzyme-powered nanomotors are an exciting technology for biomedical applications due to their ability to navigate within biological environments using endogenous fuels. However, limited studies into their collective behavior and demonstrations of tra...
Motion Administration, Intravesical Urinary Bladder Equipment Design Urease Translational Research, Biomedical Phantoms, Imaging Precision Medicine Mice Female Mice, Inbred C57BL Animals Robotics Gold Metal Nanoparticles Positron Emission Tomography Computed Tomography
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Transforming platelets into microrobots.

Science robotics Jun 10, 2020
Biocompatible cell robots powered by urea improve drug delivery through active movement.
Equipment Design Urease Motion Blood Platelets Enzymes, Immobilized Multifunctional Nanoparticles Humans Drug Delivery Systems Robotics Hydrodynamics
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Enzyme-powered Janus platelet cell robots for active and targeted drug delivery.

Science robotics Jun 10, 2020
Transforming natural cells into functional biocompatible robots capable of active movement is expected to enhance the functions of the cells and revolutionize the development of synthetic micromotors. However, present cell-based micromotor systems co...
Escherichia coli Blood Platelets Drug Delivery Systems Enzymes, Immobilized Robotics Antineoplastic Agents Humans Models, Molecular Multifunctional Nanoparticles Cell Line, Tumor Anti-Bacterial Agents Equipment Design Urease Motion
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