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HIV Infections

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Factors Associated with HIV Testing Among Participants from Substance Use Disorder Treatment Programs in the US: A Machine Learning Approach.

AIDS and behavior
HIV testing is the foundation for consolidated HIV treatment and prevention. In this study, we aim to discover the most relevant variables for predicting HIV testing uptake among substance users in substance use disorder treatment programs by applyin...

High Mobility Group Box 1 Protein Enhances HIV Replication in Newly Infected Primary T Cells.

Clinical laboratory
BACKGROUND: High-mobility group box 1 (HMGB1), a DNA-binding protein, has recently been shown to have effects on HIV replication, but the effects are dependent on the cell type and the timing of infection. Using human primary T cells, this study aime...

[Young women with HIV infection acquired by vertical transmission: Expectations of having uninfected children].

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia
INTRODUCTION: Pediatric antiretroviral therapy (ART), changed the prognosis of the disease, allowing young women infected by vertical transmission (TV) to be pregnant without risk for their fetus of acquiring this infection.

[Prevalence of potential drug-drug interactions involving antiretroviral drugs in Buenos Aires, Argentina].

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia
INTRODUCTION: Antiretroviral agents (ARVs) have a high potential for drug interactions. However, the prevalence and risk factors for clinically significant drug-drug interactions (CSDDIs) with ARVs from Latin American countries is unknown.

Virological and immunological outcomes to antiretroviral therapy in HIV-infected patients of an academic medical center in Chile.

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia
INTRODUCTION: Red Salud UC is an Academic health network where HIV-infected patients from the public and private health system are followed by a multidisplinary team.

Unsupervised selection of RV144 HIV vaccine-induced antibody features correlated to natural killer cell-mediated cytotoxic reactions.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
HIV-1 vaccine injection has been shown less effective due to the diversity of antigens. Increasing the knowledge of the associations between immune system and virus would ultimately result in producing effective vaccines against HIV-1 virus. To incre...

Tackling the problem of HIV drug resistance.

Postepy biochemii
The virally-encoded HIV-1 protease is an effective target for antiviral drugs, however, treatment for HIV infections is limited by the prevalence of drug resistant viral mutants. In this review, we describe our three-pronged approach to analyze and c...

Computer-Aided Optimization of Combined Anti-Retroviral Therapy for HIV: New Drugs, New Drug Targets and Drug Resistance.

Current HIV research
BACKGROUND: Resistance to antiretroviral drugs is a complex and evolving area with relevant implications in the treatment of human immunodeficiency virus (HIV) infection. Several rules, algorithms and full-fledged computer programs have been develope...

Long-term Virologic Suppression Despite Presence of Resistance-associated Mutations Among Perinatally HIV-infected Youth.

The Pediatric infectious disease journal
BACKGROUND: There is limited information on long-term consequences of continuing combination antiretroviral therapy (cART) consisting of <3 active drugs in treatment-experienced youth with perinatal HIV (PHIV). This study describes the clinical outco...

[Analysis on gene sequence of HIV isolated from men who have sex with men in Beijing].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
OBJECTIVE: To analyze genetic characteristics of HIV isolated from men who have sex with men (MSM) in Beijing and predict the epidemic trend in this population.