AIMC Topic: HIV Infections

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The future of HIV diagnostics: an exemplar in infectious diseases.

The lancet. HIV
Over the past 40 years, diagnostics have become the backbone of HIV prevention, treatment, and retention in care, and are central to the achievement of UNAIDS 95-95-95 targets. Over the next decade, the global HIV response will face difficult challen...

A comparative study on TB incidence and HIVTB coinfection using machine learning models on WHO global TB dataset.

Scientific reports
Tuberculosis, a deadly and contagious disease caused by Mycobacterium tuberculosis, remains a significant global public health threat. HIV co-infection significantly increases the risk of active TB recurrence and prolongs medical treatment for tuberc...

Systematic review of infodemiology studies using artificial intelligence: social media posts on HIV preexposure prophylaxis.

AIDS (London, England)
OBJECTIVES: To explore how artificial intelligence (AI) can enhance infodemiology, which distributes and scans information in the electronic medium, to process social media posts for HIV preexposure prophylaxis (PrEP).

Role of eccentricity based topological descriptors to predict anti-HIV drugs attributes with supervised machine learning algorithms.

Computers in biology and medicine
Chemical graphs are mathematical representations of molecular structures, where atoms are represented as vertices, while chemical bonds are depicted as edges of a graph. The chemical graphs are widely used in cheminformatics to analyze molecular prop...

Monocyte distribution width (MDW) as a reliable diagnostic biomarker for sepsis in patients with HIV.

Emerging microbes & infections
Sepsis is a leading cause of death among patients with HIV, but early diagnosis remains a challenge. This study evaluates the diagnostic performance of monocyte distribution width (MDW) in detecting sepsis in patients with HIV. A prospective observat...

An explainable web application based on machine learning for predicting fragility fracture in people living with HIV: data from Beijing Ditan Hospital, China.

Frontiers in cellular and infection microbiology
PURPOSE: This study aimed to develop and validate a novel web-based calculator using machine learning algorithms to predict fragility fracture risk in People living with HIV (PLWH), who face increased morbidity and mortality from such fractures.

Predicting the immunological nonresponse to antiretroviral therapy in people living with HIV: a machine learning-based multicenter large-scale study.

Frontiers in cellular and infection microbiology
BACKGROUND: Although highly active antiretroviral therapy (HAART) has greatly enhanced the prognosis for people living with HIV (PLWH), some individuals fail to achieve adequate immune reconstitution, known as immunological nonresponse (INR), which i...

Evolving strategies in the diagnosis and treatment of HIV-associated neurocognitive disorders.

Reviews in the neurosciences
Despite significant progress in managing HIV infection, HIV - associated neurocognitive disorder (HAND) continues to be a concern even among HIV individuals with well - controlled infection. Current diagnostic strategies, primarily reliant on neurops...

Using machine learning to predict poor adherence to antiretroviral therapy among adolescents with HIV in low resource settings.

AIDS (London, England)
OBJECTIVES: Achieving optimal adherence to antiretroviral therapy (ART) and viral suppression is still insufficient for attaining the UNAIDS 95-95-95 target of 2030, especially among adolescents with HIV (AWHIV). This study sought to develop a model ...

Disease diagnostics using machine learning of B cell and T cell receptor sequences.

Science (New York, N.Y.)
Clinical diagnosis typically incorporates physical examination, patient history, various laboratory tests, and imaging studies but makes limited use of the human immune system's own record of antigen exposures encoded by receptors on B cells and T ce...