BACKGROUND: Drug-drug interactions (DDIs) are a major concern, especially for older adults taking multiple medications. Although Health Canada and the US Food and Drug Administration (FDA) use population-based studies to identify adverse drug events,...
BACKGROUND: Machine learning (ML) has shown great potential in recognizing complex disease patterns and supporting clinical decision-making. Diabetic foot ulcers (DFUs) represent a significant multifactorial medical problem with high incidence and se...
BACKGROUND: Head and neck cancer (HNC) survivors face profound functional and quality-of-life deficits due to disease- and treatment-related sequelae, ranging from mild fatigue to debilitating dysphagia. Wearable technology, by monitoring biometric d...
BACKGROUND: Offline reinforcement learning (RL) has been increasingly applied to clinical decision-making problems. However, due to the lack of a standardized pipeline, prior work often relied on strategies that may lead to overfitted policies and in...
This paper explores the integration of generative artificial intelligence (AI) into psychotherapeutic practice through the lens of mentalization theory, with a particular focus on epistemic trust-a critical relational mechanism that facilitates psych...
PURPOSE OF REVIEW: This review explores the unique anatomy and pathophysiology of pericardial fat (including both epicardial adipose tissue [EAT] and paracardial fat), its clinical significance, and its potential role as a therapeutic target. It addr...
BACKGROUND: Nuclear imaging is the cornerstone of clinical practice across many disciplines. Few innovations in imaging have addressed occupational health of radiographers exposed to radiation in their daily work. In this proof-of-concept study, we h...
The rapid evolution of large language models (LLMs) in the medical field, particularly in automating medical tasks and supporting diagnosis and treatment, has shown promising potential. However, their accuracy, comprehensiveness, and safety in managi...
Archives of orthopaedic and trauma surgery
Oct 10, 2025
AIMS: The aim of this retrospective study was the evaluation of the patient-reported and radiological outcome of intravenous Iloprost therapy in the treatment of spontaneous osteonecrosis of the knee (SONK).
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