Clinical research and practice in the 21st century is poised to be transformed by analysis of computable electronic medical records and population-level genome-scale patient profiles. Genomic data capture genetic and environmental state, providing in...
IEEE transactions on bio-medical engineering
Jun 1, 2018
OBJECTIVE: In this paper, we accurately detect the state-sequence first heart sound (S1)-systole-second heart sound (S2)-diastole, i.e., the positions of S1 and S2, in heart sound recordings. We propose an event detection approach without explicitly ...
IEEE transactions on bio-medical engineering
Jun 1, 2018
OBJECTIVE: Computer-aided estimation of brain connectivity aims to reveal information propagation in brain automatically, which has great potential in clinical applications, e.g., epilepsy foci diagnosis. Granger causality is an effective tool for di...
Journal of medical toxicology : official journal of the American College of Medical Toxicology
Jun 1, 2018
Adverse drug events (ADEs) are common and have serious consequences in older adults. ED visits are opportunities to identify and alter the course of such vulnerable patients. Current practice, however, is limited by inaccurate reporting of medication...
Targeted prostate biopsy, incorporating multi-parametric magnetic resonance imaging (mp-MRI) and its registration with ultrasound, is currently the state-of-the-art in prostate cancer diagnosis. The registration process in most targeted biopsy system...
OBJECTIVE: An ability to map seizure-generating brain tissue, i.e. the seizure onset zone (SOZ), without recording actual seizures could reduce the duration of invasive EEG monitoring for patients with drug-resistant epilepsy. A widely-adopted practi...
INTRODUCTION: The FDA Adverse Event Reporting System (FAERS) is a primary data source for identifying unlabeled adverse events (AEs) in a drug or biologic drug product's postmarketing phase. Many AE reports must be reviewed by drug safety experts to ...
IMPORTANCE: Multiparametric magnetic resonance imaging (MRI) enhances detection and risk stratification for significant prostate cancer but is time-consuming (approximately 40 minutes) and expensive. Rapid and simpler (approximately 15-minute) bipara...
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