The increasing complexity of cancer diagnostics and treatment selection has placed a growing burden on pathologists, particularly in the evaluation of immunohistochemical (IHC) biomarkers. In gastroesophageal cancers (GEC), both adenocarcinoma and sq...
Drug-Target Interaction (DTI) prediction plays a pivotal role in accelerating drug discovery and development by identifying novel interactions between drugs and targets. Most previous studies on Drug-Protein Pair (DPP) networks have primarily focused...
OBJECTIVE: Recently, there has been growing interest in analyzing large amounts of Electronic Health Record (EHR) data. Patient outcome prediction is a major area of interest in EHR analysis that focuses on predicting the future health status of pati...
PURPOSE: Human-centered artificial intelligence (AI) plays a crucial role in medical research. This paper evaluates the impact of human expertise in AI systems, using dementia prediction as a case study. Specifically, plasma phospho-tau181 (ptau181) ...
Surface-enhanced Raman spectroscopy (SERS) has emerged as a transformative analytical tool in disease diagnostics, offering unparalleled sensitivity and molecular fingerprinting capabilities. However, its clinical translation is hindered by the inher...
This paper introduces an efficient sub-model ensemble framework aimed at enhancing the interpretability of medical deep learning models, thus increasing their clinical applicability. By generating uncertainty maps, this framework enables end-users to...
In modern healthcare, telemedicine, health records, and AI-driven diagnostics depend on medical image watermarking to secure chest X-rays for pneumonia diagnosis, ensuring data integrity, confidentiality, and authenticity. A 2024 study found over 70 ...
BACKGROUND/PURPOSE: Multiple parametric imaging in positron emission tomography (PET) is challenging due to the noisy dynamic data and the complex mapping to kinetic parameters. Although methods like direct parametric reconstruction have been propose...
INTRODUCTION: Computer vision (CV) has had a transformative impact in biomedical fields such as radiology, dermatology, and pathology. Its real-world adoption in surgical applications, however, remains limited. We review the current state-of-the-art ...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Jun 2, 2025
BACKGROUND: Multiparametric Magnetic Resonance Imaging (mpMRI) is the gold standard for diagnosing brain tumors, especially gliomas, which are difficult to segment due to their heterogeneity and varied sub-regions. While manual segmentation is time-c...
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