OBJECTIVES: It remains debated whether gestational hypertension (GH) and pre-eclampsia (PE) are distinct entities or different spectra of the same disease. Currently, comparative studies of risk factors for GH and PE in the same population are limite...
Biochemical changes in the cervix during labor are not well understood. This gap in knowledge is significant, as understanding the precise biochemical processes can provide critical insights into the mechanisms of labor and potentially inform better ...
BACKGROUND: Hypertensive disorders of pregnancy (HDP) are a major contributor to maternal morbidity, mortality, and accelerated cardiovascular (CV) disease. Comorbid conditions are likely important predictors of CV risk in pregnant people. Currently,...
American journal of obstetrics and gynecology
Feb 27, 2024
BACKGROUND: The great obstetrical syndromes of fetal growth restriction and hypertensive disorders of pregnancy can occur individually or be interrelated. Placental pathologic findings often overlap between these conditions, regardless of whether 1 o...
INTRODUCTION: Early prediction of preeclampsia (PE) is of universal importance in controlling the disease process. Our study aimed to assess the feasibility of using retinal fundus images to predict preeclampsia via deep learning in singleton pregnan...
Expert review of cardiovascular therapy
Jun 21, 2023
INTRODUCTION: Guidelines advise ongoing follow-up of patients after hypertensive disorders of pregnancy (HDP) to assess cardiovascular risk and manage future patient-specific pregnancy conditions. However, there are limited tools available to monitor...
Hypertension research : official journal of the Japanese Society of Hypertension
May 9, 2023
In the first trimester of pregnancy, accurately predicting the occurrence of pregnancy-induced hypertension (PIH) is important for both identifying high-risk women and adopting early intervention. In this study, we used four machine-learning models (...
Clinical guidelines recommend several risk factors to identify women in early pregnancy at high risk of developing pregnancy-associated hypertension. However, these variables result in low predictive accuracy. Here, we developed a prediction model fo...
The elucidation of dynamic metabolomic changes during gestation is particularly important for the development of methods to evaluate pregnancy status or achieve earlier detection of pregnancy-related complications. Some studies have constructed model...
BACKGROUND: Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal and fetal mortality worldwide. Early detection and risk stratification are critical for timely intervention to prevent severe complications such as eclampsia, strok...
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