To enhance thrombolysis eligibility in acute ischemic stroke, we developed a deep learning model to estimate stroke onset within 4.5 h using diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) images. Given the variabilit...
Ischemic stroke (IS) affects 11 million people annually, posing substantial clinical and economic burdens. Current therapies remain limited by time sensitivity and variable efficacy, necessitating novel biomarkers. We developed a multi-omics framewor...
BACKGROUND: In most medical centers, particularly in primary hospitals, non-contrast computed tomography (NCCT) serves as the primary imaging modality for diagnosing acute ischemic stroke. However, due to the small density difference between the infa...
INTRODUCTION: Accurate early prognostic prediction for acute ischemic stroke (AIS) is essential for guiding personalized treatment. This study aimed to assess the predictive value of radiomics features from whole-brain and infarct cerebral blood flow...
The preferred treatment for acute ischaemic stroke (AIS) is intravenous thrombolysis (IVT) administered within 4.5 hours (h) of symptom onset. This study aimed to identify metabolomic biomarkers for distinguishing AIS patients within 4.5 h of symptom...
International journal of medical informatics
Jun 21, 2025
OBJECTIVE: Develop a two-stage, machine learning-based thrombolysis risk stratification model from existing medical datasets and electronic health records to predict the risk of early hemorrhagic transformation(HT) and in-hospital mortality(IM) follo...
Ecotoxicology and environmental safety
Jun 21, 2025
This study applied network toxicology and multimodal biological approaches integrated with machine learning to systematically identify four TCS-IS-related genes, providing a comprehensive understanding of the pathophysiological relationship between t...
PURPOSE: This study explores a multi-modal deep learning approach that integrates pre-intervention neuroimaging and clinical data to predict endovascular therapy (EVT) outcomes in acute ischemic stroke patients. To this end, consecutive stroke patien...
Software programs leveraging artificial intelligence to detect vessel occlusions are now widely available to aid in stroke triage. Given their proprietary use, there is a surprising lack of information regarding how the software works, who is using t...
Stroke is the second leading cause of death, accounting for 11% of deaths worldwide. Comparing diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) images is important for stroke diagnosis, but most studies have focused on lesion...
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